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Dosage and characterization of circulating DNA: present usage and possible applications in systemic autoimmune disorders
M Galeazzi et al.
AUTOIMMUNITY REVIEWS (2003)
About the possible origin and mechanism of circulating DNA - Apoptosis and active DNA release
M Stroun et al.
CLINICA CHIMICA ACTA (2001)
Quantitation of genomic DNA in plasma and serum samples: higher concentrations of genomic DNA found in serum than in plasma
TH Lee et al.
TRANSFUSION (2001)
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