期刊
SYNTHESIS-STUTTGART
卷 53, 期 4, 页码 587-610出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0040-1707328
关键词
N,N-dimethyl enaminones; C(sp(2))-H alpha-functionalization; cyclization reactions; C = C double bond cleavage; heterocycles
资金
- National Natural Science Foundation of China [21961018]
- Natural Science Foundation of Yunnan Province [201901T070302]
- Analytical & Testing Foundation of Kunming University of Science and Technology [2017T20130137]
- Fundamental Research Funds for Gannan Medical University [QD202001]
Enaminones, particularly N,N-dimethyl enaminones, are increasingly researched for their unique properties in organic synthesis as versatile building blocks with favorable leaving groups. Recent reports have highlighted the synthetic applications of N,N-dimethyl enaminones, with a focus on the past five years.
Enaminones are gaining increasing interest because of their unique properties and their importance in organic synthesis as versatile building blocks. N,N-Dimethyl enaminones offer a better leaving group (a dimethylamine group) than other enaminones, and allow further elaboration via a range of facile chemical transformations. Over the past five years, there have been an increasing number of reports describing the synthetic applications of N,N-dimethyl enaminones. This review provides a comprehensive overview on the synthetic applications of N,N-dimethyl enaminones that have been reported since 2016.
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