4.6 Article

Duration of anxiety disorder and its associated risk indicators: Results of a longitudinal study of the general population

期刊

DEPRESSION AND ANXIETY
卷 38, 期 3, 页码 328-336

出版社

WILEY
DOI: 10.1002/da.23103

关键词

anxiety disorder; new episode; population surveys; risk factors

资金

  1. Ministry of Health, Welfare and Sport
  2. Netherlands Organization for Health Research and Development (ZonMw)
  3. Genetic Risk and Outcome of Psychosis (GROUP) investigators

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Research on anxiety disorders in the general population shows that the disorder tends to have a chronic course, with a significant proportion of patients not recovering after 12 months. Risk factors for longer episode duration include older age, lack of paid job, higher neuroticism, more physical disorders, and worse physical functioning.
Background Data on episode duration of anxiety disorders are required for informing patients and for disease management, but such data from population studies are lacking. Methods Three-year longitudinal data were used from the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among the general adult population (N = 6646). Respondents with a new (first or recurrent) anxiety disorder were selected (n = 158). DSM-IV diagnoses were assessed with the Composite International Diagnostic Interview; the Life Chart Interview assessed episode duration and recovery rates. Results Among those with anxiety disorder, median episode duration was 7.5 months and mean duration was 15.2 months. 38.8% had not recovered at 12 months and 30.1% not at 36 months. Longer duration was associated with older age, not having a paid job, higher neuroticism, more physical disorders, and worse physical functioning. Conclusions Also, in the general population, anxiety disorder has a rather chronic course. After 12 months the cumulative recovery rate flattened. To prevent and manage chronicity, timely treatment, and chronic disease management are required. The risk indicators found may help to identify individuals with an anxiety disorder at risk for chronicity.

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