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JOURNAL OF PATHOLOGY (2009)
Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis a phase I/II study. (vol 8, pg 244, 2009)
R. K. Burt et al.
LANCET NEUROLOGY (2009)
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
Ingo Bartholomaeus et al.
NATURE (2009)
Intraclonal competition limits the fate determination of regulatory T cells in the thymus
Jhoanne L. Bautista et al.
NATURE IMMUNOLOGY (2009)
Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility
Matthew R. Lincoln et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Multiple sclerosis: major histocompatibility complexity and antigen presentation
Sreeram V. Ramagopalan et al.
GENOME MEDICINE (2009)
Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study
Richard K. Burt et al.
LANCET NEUROLOGY (2009)
Compromised CD4(+) CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
Koen Venken et al.
IMMUNOLOGY (2008)
EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-γ and IL-2
Jan D. Luenemann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla
Tom M. McCaughtry et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Natural naive CD4+CD25+CD127low regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients:: Recovery of memory treg homeostasis during disease progression
Koen Venken et al.
JOURNAL OF IMMUNOLOGY (2008)
Thymic output and peripheral T lymphocyte subsets in relapsing-remitting multiple sclerosis patients treated or not by IFN-beta
Benedicte Puissant-Lubrano et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Acetylation in nuclear receptor signaling and the role of sirtuins
Chenguang Wang et al.
MOLECULAR ENDOCRINOLOGY (2008)
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Yongzhong Liu et al.
NATURE IMMUNOLOGY (2008)
Neuronal surface antigen antibodies in limbic encephalitis - Clinical-immunologic associations
F. Graus et al.
NEUROLOGY (2008)
Crosspresentation by nonhematopoietic and direct presentation by hematopoietic cells induce central tolerance to myelin basic protein
Antoine Perchellet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
How regulatory T cells work
Dario A. A. Vignali et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Creating immune privilege: active local suppression that benefits friends, but protects foes
Andrew L. Mellor et al.
NATURE REVIEWS IMMUNOLOGY (2008)
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus
Matthieu Giraud et al.
NATURE (2007)
B-cell anergy: from transgenic models to naturally occurring anergic B cells?
John C. Cambier et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis
Jurgen Haas et al.
JOURNAL OF IMMUNOLOGY (2007)
Analyses of immunosenescent markers in patients with autoimmune disease
Marielle Thewissen et al.
CLINICAL IMMUNOLOGY (2007)
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
Katharina Aschenbrenner et al.
NATURE IMMUNOLOGY (2007)
Environmental and intrinsic factors lead to antigen unresponsiveness in CD4+ recent thymic emigrants from aged mice
Karen Clise-Dwyer et al.
JOURNAL OF IMMUNOLOGY (2007)
Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
Kassandra L. Munger et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
Mark A. Daniels et al.
NATURE (2006)
Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus
Roberto Bonasio et al.
NATURE IMMUNOLOGY (2006)
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
Ralf Gold et al.
BRAIN (2006)
Estrogen induces thymic atrophy by eliminating early thymic progenitors and inhibiting proliferation of β-selected thymocytes
Allison L. Zoller et al.
JOURNAL OF IMMUNOLOGY (2006)
Cutting edge:: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+ CD25+ T regulatory cells
Adam P. Kohm et al.
JOURNAL OF IMMUNOLOGY (2006)
Cellular and molecular events during early thymus development
G Holländer et al.
IMMUNOLOGICAL REVIEWS (2006)
Altered naive CD4 and CD8 T cell homeostasis in patients with relapsing-remitting multiple sclerosis:: thymic versus peripheral (non-thymic) mechanisms
DA Duszczyszyn et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2006)
A requirement for sustained ERK signaling during thymocyte positive selection in vivo
LK McNeil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Stiff man syndrome with thymoma
H Tanaka et al.
ANNALS OF THORACIC SURGERY (2005)
The cellular mechanism of Aire control of T cell tolerance
MS Anderson et al.
IMMUNITY (2005)
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients
PA Muraro et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
M Greter et al.
NATURE MEDICINE (2005)
Timing of birth and risk of multiple sclerosis: population based study.
CJ Willer et al.
BMJ-BRITISH MEDICAL JOURNAL (2005)
Epstein-Barr virus nuclear antigen leader protein induces expression of thymus- and activation-regulated chemokine in B cells
M Kanamori et al.
JOURNAL OF VIROLOGY (2004)
Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis
W Sun et al.
BRAIN (2004)
Predominant autoantibody production by early human B cell precursors
H Wardemann et al.
SCIENCE (2003)
Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis
A Hug et al.
JOURNAL OF IMMUNOLOGY (2003)
Dietary zinc modulates gene expression in murine thymus: Results from a comprehensive differential display screening
JB Moore et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Projection of an immunological self shadow within the thymus by the aire protein
MS Anderson et al.
SCIENCE (2002)
A functional and structural basis for TCR cross-reactivity in multiple sclerosis
HLE Lang et al.
NATURE IMMUNOLOGY (2002)
Lymphostromal interactions in thymic development and function
G Anderson et al.
NATURE REVIEWS IMMUNOLOGY (2001)
Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA)
L Al-Harthi et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2000)
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
L Klein et al.
NATURE MEDICINE (2000)
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