期刊
EUROPEAN RADIOLOGY
卷 31, 期 5, 页码 3347-3354出版社
SPRINGER
DOI: 10.1007/s00330-020-07359-7
关键词
Magnetic resonance imaging; Rectal cancer; Lymph nodes; Metastatic
资金
- Science and Technology Program of Fujian Province of China [2017D017]
- Joint Funds for the Health and Education of Fujian Province, China [2019-WJ-31]
- Institute of Respiratory Diseases, Xiamen Medical College [HXJB-06, 15]
The study concluded that T2 mapping had higher diagnostic efficacy and reproducibility compared to ADC, making it useful in differentiating metastatic from non-metastatic lymph nodes in rectal cancer.
Objectives To evaluate the diagnostic value and reproducibility of T2 mapping versus apparent diffusion coefficients (ADC) for identifying malignant lymph nodes in patients with non-mucinous rectal adenocarcinoma. Methods High-resolution magnetic resonance imaging, diffusion-weighted imaging, and T2 mapping were performed on patients with suspected metastatic lymph nodes in the mesorectum or around the superior rectal artery with a short-axis diameter of 4-10 mm. The T2 and ADC values of pathology-confirmed metastatic versus non-metastatic lymph nodes were compared using the independent-samples t test and receiver operating characteristic curves. Intra- and inter-observer reproducibility were tested. The cutoff value for T2 relaxation time was determined. Results In total, 67 lymph nodes underwent histological analysis, with 24 in the non-metastatic and 43 in the metastatic groups. Intra- and inter-observer agreements for T2 values were 0.999 and 0.998, respectively, which were higher than the ADC values of 0.924 and 0.844, respectively. The mean T2 and ADC values for metastatic lymph nodes (65 +/- 7.8 ms and 1.17 +/- 0.16 x 10(-3) mm(2)/s, respectively) were significantly lower than for benign lymph nodes(83 +/- 5.7 ms and 1.29 +/- 0.15 x 10(-3) mm(2)/s, respectively). T2 values had a higher AUC value of 0.990 than the AUC value for ADC of 0.729. With a cutoff value of 77 ms, sensitivity and specificity for T2 values were 95% and 96%, respectively. Conclusions T2 mapping had higher diagnostic efficacy and reproducibility than ADC and may be useful in differentiating metastatic from non-metastatic lymph nodes in rectal cancer.
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