Antibacterial effect of nanocurcumin inside the implant fixture: An in vitro study

Objectives: Infections after implant placement are the main reasons for the failure of implant treatments. The present study aimed to evaluate the antibacterial effects of nanocurcumin inside the implant fixture against Escherichia coli, Staphylococcus aureus, and Enterococcus faecalis. Materials and Methods: Twenty seven implants were classified in three groups for testing the antibacterial effect of nanocurcumin, chlorhexidine (as negative control), and distilled water (as negative control). Each group was then divided into three subgroups to study the effect of the applied torque on the antimicrobial effect of nanocurcumin. All implant abutment assemblies were submerged in bacteria suspension and were incubated at 37 degrees C for 24 hours. The contents of each implant were removed to count the colony of bacteria on the surface of plates containing nutrient agar. Results: Results indicated that the inhibitory rate of bacteria by nanocurcumin was above 99% in all bacteria. Besides, by increasing the amount of applied torque from 10 to 35 N.cm, the CFU of bacteria in exposure to nanocurcumin significantly were decreased (p-value < 0.01). Conclusion: The results of this study revealed that nanocurcumin can be used inside the implant fixture in order to use antimicrobial effects and further stabilization and success of the implant.

Automated summary

The study aimed to evaluate the antibacterial effects of nanocurcumin inside the implant fixture, showing that nanocurcumin inhibited bacteria by over 99% and increasing torque significantly decreased CFU of bacteria exposed to nanocurcumin. These findings suggest that nanocurcumin can be used inside implants for antimicrobial effects and implant stabilization.