4.3 Review

Insights into normothermic treatment with direct irradiation of atmospheric pressure plasma for biological applications

期刊

出版社

IOP PUBLISHING LTD

关键词

nonequilibrium atmospheric pressure plasma; direct irradiation; biological application; normothermic plasma treatment

资金

  1. National Institutes of Natural Sciences (NINS) program of Promoting Research by Networking among Institutions [01411702]
  2. joint usage/research program of the Center for Low-temperature Plasma Sciences, Nagoya University

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This review highlights the importance of gas temperature control in nonequilibrium atmospheric pressure plasmas for direct plasma treatments of living organisms. It discusses critical parameters associated with these treatments and assesses the current status and prospects for further developments in understanding the interactions between plasma and living organisms, emphasizing the significance of normothermic plasma treatment.
Characterizing the interactions between plasma and living organisms has become a multidisciplinary topic in the field of low-temperature plasma science and technology. Living organisms are hierarchically comprised of cells, tissues, organs, and organ systems. Adaptive responses are systematically controlled by the state of the surrounding environment, such as when living organisms are irradiated with discharge plasma. This review is written from a biological perspective and focuses on the importance of gas temperature control in nonequilibrium atmospheric pressure plasmas. We discuss the critical parameters associated with direct plasma treatments of living organisms. This review provides an assessment of the status of this research field and addresses the prospects for further developments in understanding the interactions between plasma and living organisms. We address the importance and necessity of normothermic plasma treatment, where an experimental system involving living organisms is controlled at an optimal temperature, which plays a significant role in plasma biology.

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