期刊
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY
卷 11, 期 3, 页码 10729-10738出版社
BIOINTERFACE RESEARCH APPLIED CHEMISTRY
DOI: 10.33263/BRIAC113.1072910738
关键词
Heracleum; hogweed; coumarin; steroids; essential oil
资金
- Urmia University of Medical Sciences
Heracleum lasiopetalum, native to Iran and belonging to the Apiaceae family, is used for its fruits and seeds as spices and food additives. The plant has been found to contain important natural products such as steroids and coumarins, suggesting potential applications in the cosmetics and pharmaceutical industries.
Heracleum lasiopetalum belongs to the Apiaceae family and is native to Iran. The fruits and seeds of the herb are used as spices and food additives. The genus has significant pharmacological activities. In order to study the phytochemicals of H. lasiopetalum, aerial parts of the plant were conducted to a separation process. Different chromatographic techniques were employed for the purification of its natural products. The chemical structure of the isolated metabolites was determined using spectroscopic methods such as NMR and IR as well as elemental analysis. Moreover, the essential oil composition of roots and aerial parts of the herb were characterized using GC-MS analysis. The purified compounds were elucidated as beta-sitosterol (plant steroid) and suberosin (coumarin). Identification of essential oil composition showed that 17 and 12 volatile compounds were present in the aerial parts and roots of the herb, respectively. Germacrene D, falcarinol, farnesol, and octanal were found as the major components. Findings showed that H. lasiopetalum contains important natural products such as steroids, coumarins, monoterpenoids, and sesquiterpenoids. According to its bioactive products, this herb could be considered for more applications in the cosmetics and pharmaceutical industries.
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