期刊
ADVANCED PHARMACEUTICAL BULLETIN
卷 11, 期 1, 页码 111-119出版社
TABRIZ UNIV MEDICAL SCIENCES & HEALTH SERVICES
DOI: 10.34172/apb.2021.012
关键词
Cyclic voltammetry; Carbon nanotube paste electrode; SDS; Isatin; Resorcinol
The study successfully demonstrated the oxidation of IS using SDS modified carbon nano tube paste electrode, showing superior stability, selectivity, and sensitivity compared to bare carbon nano tube paste electrode. The process was found to be diffusion controlled and linearly increased with the concentration of IS.
Purpose: Isatin (IS) is a synthetically significant heterocyclic moiety with an influential pharmacodynamic indole nucleus and hence the electrocatalytic property of has been investigated. Methods: The electrochemical analysis was demonstrated by cyclic voltammetry (CV) in the potential window of 0.2 V to 1.4 V using sodium dodecyl sulfate (SDS) modified carbon nano tube paste electrode (SDSMCNTPE) over a pH range of 6 to 8.5 in 0.2 M phosphate buffer solution (PBS). Surface morphology was studied by using Field emission-scanning electron microscopy (FESEM). Results: The CV study discloses that under ideal condition oxidation of IS arises at a potential of 0.970 V accompanied with an exceptional stability, selectivity and sensitivity for the resultant SDSMCNTPE contrasting to bare carbon nano tube paste electrode (BCNTPE). Individual parameters like electrode surface area, effect of surfactant, detection limit, simultaneous detection of IS and resorcinol (RC) were studied at a scan rate of 0.1 V/s. Scan rate study uncovers the process is diffusion controlled. The oxidation peak current amplified linearly with the surge in concentration of IS under ideal condition. Detection limit (LOD) and limit of quantification (LOQ) in the solution of optimum pH (7.5) at a scan rate of 0.100V/s is 2.4x10(-7) M and 8.2 x 10(-7) M respectively. Conclusion: The proposed electrode portrays excellent repeatability, reproducibility and reliability to resistant electrode fouling.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据