期刊
CHEMICAL COMMUNICATIONS
卷 57, 期 2, 页码 255-258出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc07355e
关键词
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资金
- National Key R&D Program of China [2018YFE0205400]
- National Natural Science Foundation of China [21673056, 21972033, 21961142022]
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety [NSKF202006]
- China Post-doctoral Science Foundation [2019M652361]
- Postdoctoral Innovation Program of Shandong Province [201903012]
Polydopamine nanoparticles were utilized to stabilize a nano-Pt catalyst for relieving tumor hypoxia in photodynamic therapy (PDT). In addition to serving as a carrier for nano-Pt and photosensitizers, polydopamine also acted as a photothermal reagent in photothermal therapy (PTT). The combined PDT and PTT mechanism presented an enhanced anti-tumor therapy effect.
Polydopamine nanoparticles were used to stabilize a nano-Pt catalyst to relieve tumour hypoxia in photodynamic therapy (PDT). Polydopamine not only provides a platform for carrying nano-Pt and photosensitizers but is also used as a photothermal reagent for photothermal therapy (PTT). The system presented an enhanced anti-tumor therapy effect through a combined PDT and PTT mechanism.
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