期刊
NUCLEIC ACIDS RESEARCH
卷 49, 期 D1, 页码 D344-D354出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkaa977
关键词
-
资金
- Wellcome [108433/Z/15/Z]
- Biotechnology and Biological Sciences Research Council [BB/T010541/1, BB/S020381/1, BB/N00521X/1, BB/N019172/1]
- National Science Foundation, Division of Biological Infrastructure [1458808]
- ELIXIR, the research infrastructure for life-science data
- European Molecular Biology Laboratory core funds
- Intramural Research Program of the National Library of Medicine at National Institutes of Health/DHHS
- Research Councils UK (RCUK)
- Open Targets
- Direct For Biological Sciences
- Div Of Biological Infrastructure [1458808] Funding Source: National Science Foundation
- BBSRC [BB/R014892/1, BB/N00521X/1, BB/N019431/2, BB/N019172/1, BB/T010541/1, BB/S020381/1] Funding Source: UKRI
- MRC [MC_UP_1201/14] Funding Source: UKRI
- Wellcome Trust [108433/Z/15/Z] Funding Source: Wellcome Trust
InterPro database offers a comprehensive classification of protein sequences and is a widely used resource for protein family annotation. Its software InterProScan allows users to search protein and nucleic acid sequences against InterPro's signatures.
The InterPro database (https://www.ebi.ac.uk/interpro/) provides an integrative classification of protein sequences into families, and identifies functionally important domains and conserved sites. InterProScan is the underlying software that allows protein and nucleic acid sequences to be searched against InterPro's signatures. Signatures are predictive models which describe protein families, domains or sites, and are provided by multiple databases. InterPro combines signatures representing equivalent families, domains or sites, and provides additional information such as descriptions, literature references and Gene Ontology (GO) terms, to produce a comprehensive resource for protein classification. Founded in 1999, InterPro has become one of the most widely used resources for protein family annotation. Here, we report the status of InterPro (version 81.0) in its 20th year of operation, and its associated software, including updates to database content, the release of a new website and REST API, and performance improvements in InterProScan.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据