期刊
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
卷 53, 期 3, 页码 273-282出版社
SCIENCE PRESS
DOI: 10.1093/abbs/gmaa176
关键词
COVID-19; SARS-CoV-2; cardiovascular disease; cardiovascular injury; treatment
资金
- National Natural Sciences Foundation of China [81970390, 81470569]
- Innovation Foundation for Postgraduate of Hunan Province [CX2017B550, CX2016B490]
- Natural Science Foundation of Hunan Province, China [2018JJ2341]
- National College Students Innovation and Entrepreneurship Fund [201710555015, 201710555010]
The COVID-19 pandemic caused by the novel coronavirus has significant impact on cardiovascular health and can lead to various cardiac complications. Urgent research is needed to identify effective treatment methods.
The coronavirus disease-2019 (COVID-19) caused by the novel coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has rapidly developed into a global pneumonia pandemic. Cardiovascular disease is the major comorbidity of COVID-19 patients and is closely related to the severity of COVID-19. SARS-CoV-2 infection can directly or indirectly cause a series of cardiac complications, including acute myocardial injury and myocarditis, heart failure and cardiac arrest, arrhythmia, acute myocardial infarction, cardiogenic shock, Takotsubo cardiomyopathy, and coagulation abnormalities. Intensive research on the SARS-CoV-2-associated cardiovascular complications is urgently needed to elucidate its exact mechanism and to identify potential drug targets, which will help to formulate effective prevention and treatment strategies. Hence, this review will summarize recent progress regarding the effects of COVID-19 on the cardiovascular system and describe the underlying mechanism of cardiovascular injury caused by SARS-CoV-2.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据