期刊
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
卷 46, 期 4, 页码 797-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.gtc.2017.08.011
关键词
Crohn disease; Ulcerative colitis; Diet; Nutrition; Deficiency; Supplementation
资金
- NIDDK NIH HHS [R37 DK033209, R01 DK041274, R01 DK109711, R01 DK033209] Funding Source: Medline
Indiscriminate use of multivitamin/mineral supplements in the general population may be misguided, but patients with chronic Inflammatory Bowel Diseases (IBD) should be monitored and compensated for nutritional deficiencies. Mechanistic links between vitamin/mineral deficiencies and IBD pathology has been found for some micronutrients and normalizing their levels is clinically beneficial. Others, like vitamin A, although instinctively desirable, produced disappointing results. Restoring normal levels of the selected micronutrients requires elevated doses to compensate for defects in absorptive or signaling mechanisms. This article describes some aspects of vitamin and mineral deficiencies in IBD, and summarizes pros and cons of supplementation.
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