期刊
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
卷 46, 期 4, 页码 783-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.gtc.2017.08.004
关键词
Inflammatory bowel disease; Ulcerative colitis; Crohn disease; Prebiotics; Fiber
Dietary fiber, specifically prebiotics, is the primary source of energy for the gut microbiota and thus has the potential to beneficially modify microbiota composition. Prebiotics have been used in in vitro studies and with animal models of colitis with largely positive results. Human studies are few and have been conducted with only a few select prebiotics, primarily fructan-containing fibers. Although disease activity and inflammatory markers have improved, more needs to be learned about the specific prebiotic compounds and how they can be used to best improve the gut microbiota to counter changes induced by inflammatory bowel disease.
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