期刊
ORGANIC CHEMISTRY FRONTIERS
卷 8, 期 1, 页码 169-191出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0qo01157f
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资金
- Graduate School of University of Wisconsin-Milwaukee [RGI-101X351]
The discovery of 3-hydroxy-2-aryl acrylate has been a significant breakthrough, serving as a pivotal building block in the synthesis of bioactive compounds and essential drugs. This scaffold, with its electrophilic and nucleophilic centers, plays a crucial role in various chemical fields.
The discovery of the 3-hydroxy-2-aryl acrylate was a significant breakthrough in the field of organic and medicinal chemistry. Due to the presence of both electrophilic and nucleophilic centers, this scaffold acts as a fascinating building block of many bioactive compounds. More importantly, 3-hydroxy-2-aryl acrylate is a vital precursor in the synthesis of natural products and in the development of essential drugs. In this first review, we outline different approaches for preparing 3-hydroxy-2-aryl acrylate with mechanisms and its application in a variety of chemical fields.
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