期刊
CHINESE CHEMICAL LETTERS
卷 32, 期 1, 页码 243-257出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2020.11.029
关键词
Polymeric micelles; Drug delivery; Preparation; Clinical application; Challenges
资金
- Fundamental Research Funds for the Central Universities [201964018]
- National Natural Science Foundation of China [31872754]
- Qingdao Program for Original Innovation and Fundamental Research [18-2-2-73-jch]
Polymeric nanomedicine, especially polymeric micelles (PM) with nanoscale size, shows promising physical and biological advantages such as excellent solubility, pharmacokinetics, efficacy, and lower toxicity. PM has garnered increasing interest in research and clinical applications, with good clinical outcomes but also facing challenges.
Polymeric nanomedicine is a promising and rapidly evolving field. Among the different polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and biological advantages including excellent solubility and pharmacokinetics, enhanced efficacy and lower toxicity. PM has garnered increasing interest in research and in the clinic. This review will highlight the clinical outcomes of several PM-based formulations, and further summarized their preparation methods, strengths and challenges. (C) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据