3.8 Article

Evaluation of In-Office Cryoablation of Posterior Nasal Nerves for the Treatment of Rhinitis

期刊

ALLERGY & RHINOLOGY
卷 12, 期 -, 页码 -

出版社

SAGE PUBLICATIONS INC
DOI: 10.1177/2152656720988565

关键词

cryoablation; cryosurgery; cryosurgical ablation; posterior nasal nerve; rhinitis; rhinorrhea; congestion

向作者/读者索取更多资源

The study demonstrated the effectiveness of cryoablation of the PNN in improving symptoms of chronic rhinitis, with patients experiencing sustained improvement over a year and reducing the need for nasal sprays.
Background Chronic rhinitis is a common condition generally treated with medical therapies. However, 10-22% of patients are refractory to medical therapies. A cryotherapy handheld device targeting the postganglionic nerve fibers of the posterior nasal nerve (PNN) now serves as an additional option for therapy. This study evaluates the efficacy of the cryosurgical ablation device of the PNN in the clinic setting. Methods This was a prospective single-arm trial of 24 adult patients at seven locations within a large health maintenance organization. Patients with chronic rhinitis that failed medical therapy were offered an in-office cryoablation of PNN. Patients completed the Total Nasal Symptom Score (TNSS) questionnaire consisting of 5 items reported based on the previous 12 hours and 2 weeks at the following time points: pre-treatment, 30 days, 90 days and 1 year post-treatment. Results Following cryoablation of the PNN, the TNSS 12-hour symptom score improved from 6.92 (+/- 2.9) to 3.17 (+/- 2.4, P < 0.001) at 30 days, 2.92 (+/- 1.4, P < 0.001) at 90 days and 3.08 (+/- 2.6, P < 0.001) at 1 year post treatment. Similar results were noted for the 2 weeks scores improving from 7.75 (+/- 3.1) to 3.79 (+/- 2.1, P < 0.001) at 30 days, 3.88 (+/- 1.9, P < 0.001) at 90 days and 3.76 (+/- 2.1, P < 0.001) at 1 year post-treatment. 64.7% of respondents stated the procedure decreased or eliminated nasal sprays. Conclusions Our independent evaluation of cryoablation of the PNN shows improvement in nasal symptoms over a 1 year period and is consistent with other published data.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

3.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据