相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research
Daniel S. Quintana et al.
MOLECULAR PSYCHIATRY (2021)
Memory advancement by intranasal insulin in type 2 diabetes (MemAID) randomized controlled clinical trial: Design, methods and rationale
B. Galindo-Mendez et al.
CONTEMPORARY CLINICAL TRIALS (2020)
Intranasal Insulin: a Treatment Strategy for Addiction
Bhavani Kashyap et al.
NEUROTHERAPEUTICS (2020)
Insulin and Exendin-4 Reduced Mutated Huntingtin Accumulation in Neuronal Cells
Silvia Rea et al.
FRONTIERS IN PHARMACOLOGY (2020)
ApoE and cerebral insulin: Trafficking, receptors, and resistance
Elizabeth M. Rhea et al.
NEUROBIOLOGY OF DISEASE (2020)
Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function
Zoe Arvanitakis et al.
ANNALS OF NEUROLOGY (2020)
Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia A Randomized Clinical Trial
Suzanne Craft et al.
JAMA NEUROLOGY (2020)
Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons
Hilaree N. Frazier et al.
FRONTIERS IN NEUROSCIENCE (2020)
Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases
Yu Su et al.
FRONTIERS IN PHARMACOLOGY (2020)
Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus with Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia
Timo Pekkala et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
Brain insulin resistance in Alzheimer's disease and related disorders: mechanisms and therapeutic approaches
Derek Kellar et al.
LANCET NEUROLOGY (2020)
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
Stephen C. Cunnane et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Glucose transporters in brain in health and disease
Hermann Koepsell
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2020)
Sex and gender: modifiers of health, disease, and medicine
Franck Mauvais-Jarvis et al.
LANCET (2020)
Role of Insulin in Neurotrauma and Neurodegeneration: A Review
Michael Shaughness et al.
FRONTIERS IN NEUROSCIENCE (2020)
Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease
Eugenio Barone et al.
MOLECULAR NEUROBIOLOGY (2019)
Broadening the definition of brain insulin resistance in aging and Alzheimer's disease
Hilaree N. Frazier et al.
EXPERIMENTAL NEUROLOGY (2019)
Understanding the link between insulin resistance and Alzheimer's disease: Insights from animal models
Natalia de M. Lyra e Silva et al.
EXPERIMENTAL NEUROLOGY (2019)
Distribution of insulin in trigeminal nerve and brain after intranasal administration
Jeffrey J. Lochhead et al.
SCIENTIFIC REPORTS (2019)
Characterisation of nasal devices for delivery of insulin to the brain and evaluation in humans using functional magnetic resonance imaging
Jed Wingrove et al.
JOURNAL OF CONTROLLED RELEASE (2019)
Safety and preliminary efficacy of intranasal insulin for cognitive impairment in Parkinson disease and multiple system atrophy: A double-blinded placebo-controlled pilot study
Peter Novak et al.
PLOS ONE (2019)
Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer's Disease
Christian Holscher
FRONTIERS IN AGING NEUROSCIENCE (2019)
Metformin Improves Learning and Memory in the SAMP8 Mouse Model of Alzheimer's Disease
Susan A. Farr et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
O-GlcNAcylation of Amyloid-β Protein Precursor by Insulin Signaling Reduces Amyloid-β Production
Oh Hoon Kwon et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
Extracellular Vesicle Biomarkers Track Cognitive Changes Following Intranasal Insulin in Alzheimer's Disease
Maja Mustapic et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
Association between diabetes and mood disorders and the potential use of anti-hyperglycemic agents as antidepressants
Ruth B. Grigolon et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2019)
Chronic synaptic insulin resistance after traumatic brain injury abolishes insulin protection from amyloid beta and tau oligomer-induced synaptic dysfunction
Whitney Franklin et al.
SCIENTIFIC REPORTS (2019)
Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging
Dimitrios Kapogiannis et al.
JAMA NEUROLOGY (2019)
Mechanisms of systems memory consolidation during sleep
Jens G. Klinzing et al.
NATURE NEUROSCIENCE (2019)
Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway
Sami Gabbouj et al.
FRONTIERS IN NEUROSCIENCE (2019)
Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline
Matteo Spinelli et al.
FRONTIERS IN NEUROSCIENCE (2019)
Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep
Nina E. Fultz et al.
SCIENCE (2019)
Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer's and Parkinson's Diseases
Andre F. Batista et al.
CNS DRUGS (2019)
Enhanced intranasal insulin delivery by formulations and tumor protein-derived protein transduction domain as an absorption enhancer
Nam Ah Kim et al.
JOURNAL OF CONTROLLED RELEASE (2019)
Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer's disease
Brendan P. Lucey et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
2019 Alzheimer's disease facts and figures
Joseph Gaugler et al.
ALZHEIMERS & DEMENTIA (2019)
The TOMMORROW study: Design of an Alzheimer's disease delay-of-onset clinical trial
Daniel K. Burns et al.
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS (2019)
Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease
Stefan L. C. Geijselaers et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Insulin modulates hippocampally-mediated spatial working memory via glucose transporter-4
J. Pearson-Leary et al.
BEHAVIOURAL BRAIN RESEARCH (2018)
Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice
Zhenri Ou et al.
BRAIN BEHAVIOR AND IMMUNITY (2018)
Safety of intranasal human insulin: A review
Vera Schmid et al.
DIABETES OBESITY & METABOLISM (2018)
Comparative efficacy and acceptability of antidiabetic agents for Alzheimer's disease and mild cognitive impairment: A systematic review and network meta-analysis
Bing Cao et al.
DIABETES OBESITY & METABOLISM (2018)
Importance of the brain corticosteroid receptor balance in metaplasticity, cognitive performance and neuro-inflammation
E. R. de Kloet et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2018)
Intranasal insulin in Alzheimer's dementia or mild cognitive impairment: a systematic review
Konstantinos Ioannis Avgerinos et al.
JOURNAL OF NEUROLOGY (2018)
Mechanism of intranasal drug delivery directly to the brain
Tyler P. Crowe et al.
LIFE SCIENCES (2018)
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
Steven E. Arnold et al.
NATURE REVIEWS NEUROLOGY (2018)
Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation
Laura L. Ekblad et al.
NEUROLOGY (2018)
Metabolic Syndrome and cognitive decline in the elderly: A systematic review
Naima Assuncao et al.
PLOS ONE (2018)
Insulin Resistance as a Therapeutic Target in the Treatment of Alzheimer's Disease: A State-of-the-Art Review
Christian Benedict et al.
FRONTIERS IN NEUROSCIENCE (2018)
Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
Sreemathi Logan et al.
MOLECULAR METABOLISM (2018)
Focused ultrasound combined with microbubble-mediated intranasal delivery of gold nanoclusters to the brain
Dezhuang Ye et al.
JOURNAL OF CONTROLLED RELEASE (2018)
Odor Sensitivity After Intranasal Insulin Application Is Modulated by Gender
Rea Rodriguez-Raecke et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Metabolic and Cognitive Outcomes of Subchronic Once-Daily Intranasal Insulin Administration in Healthy Men
Yvonne Ritze et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Positron Emission Tomography Assessment of the Intranasal Delivery Route for Orexin A
Genevieve C. Van de Bittner et al.
ACS CHEMICAL NEUROSCIENCE (2018)
The neuronal insulin receptor in its environment
Matthias Gralle
JOURNAL OF NEUROCHEMISTRY (2017)
Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer's Disease Biomarkers: A Pilot Clinical Trial
Suzanne Craft et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Relationships of Dietary Patterns, Foods, and Micro- and Macronutrients with Alzheimer's Disease and Late-Life Cognitive Disorders: A Systematic Review
Vincenzo Solfrizzi et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Intranasal insulin treatment of an experimental model of moderate traumatic brain injury
Fiona Brabazon et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)
Intranasal insulin decreases circulating cortisol concentrations during early sleep in elderly humans
Matthias Thienel et al.
NEUROBIOLOGY OF AGING (2017)
Insulin resistance among obese middle-aged is associated with decreased cerebrovascular reactivity
Olivia H. Frosch et al.
NEUROLOGY (2017)
Current findings on the role of oxytocin in the regulation of food intake
Maartje S. Spetter et al.
PHYSIOLOGY & BEHAVIOR (2017)
Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease
Jonathan Cedernaes et al.
SLEEP MEDICINE REVIEWS (2017)
Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults
Simon M. Laws et al.
SCIENTIFIC REPORTS (2017)
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease A Meta-analysis
Scott C. Neu et al.
JAMA NEUROLOGY (2017)
Long-term treatment with intranasal insulin ameliorates cognitive impairment, tau hyperphosphorylation, and microglial activation in a streptozotocin-induced Alzheimer's rat model
Zhangyu Guo et al.
SCIENTIFIC REPORTS (2017)
The worldwide costs of dementia 2015 and comparisons with 2010
Anders Wimo et al.
ALZHEIMERS & DEMENTIA (2017)
Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study
Aaron M. Koenig et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2017)
Central Nervous Insulin Signaling in Sleep-Associated Memory Formation and Neuroendocrine Regulation
Gordon B. Feld et al.
NEUROPSYCHOPHARMACOLOGY (2016)
Metformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical Trial
Jose A. Luchsinger et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Changes in insulin and insulin signaling in Alzheimer's disease: cause or consequence?
Molly Stanley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
INTRANASAL INSULIN PROTECTS AGAINST SUBSTANTIA NIGRA DOPAMINERGIC NEURONAL LOSS AND ALLEVIATES MOTOR DEFICITS INDUCED BY 6-OHDA IN RATS
Y. Pang et al.
NEUROSCIENCE (2016)
BRAIN INSULIN RESISTANCE AT THE CROSSROADS OF METABOLIC AND COGNITIVE DISORDERS IN HUMANS
Stephanie Kullmann et al.
PHYSIOLOGICAL REVIEWS (2016)
Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia
Rosebud O. Roberts et al.
JAMA NEUROLOGY (2016)
Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24 h) hippocampal LIP and in LTD facilitated by novel object-place learning and recognition in mice
Jinzhong Jeremy Goh et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Insulin Modulates In Vitro Secretion of Cytokines and Cytotoxins by Human Glial Cells
Lindsay J. Spielman et al.
CURRENT ALZHEIMER RESEARCH (2015)
Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity
Claudia A. Grillo et al.
DIABETES (2015)
Central Insulin Administration Improves Odor-Cued Reactivation of Spatial Memory in Young Men
Yvonne F. Bruenner et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)
Brain delivery of insulin boosted by intranasal coadministration with cell-penetrating peptides
Noriyasu Kamei et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type
Julius Popp et al.
NEUROBIOLOGY OF AGING (2015)
Hypothalamic-pituitary-adrenal axis dysregulation and cortisol activity in obesity: A systematic review
Angela C. Incollingo Rodriguez et al.
PSYCHONEUROENDOCRINOLOGY (2015)
The Impact of Diabetes on Cerebral Structure and Function
Elizabeth R. Seaquist
PSYCHOSOMATIC MEDICINE (2015)
Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors
Claire J. Garwood et al.
MOLECULAR BRAIN (2015)
Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle-Aged Adults at Risk for Alzheimer Disease
Auriel A. Willette et al.
JAMA NEUROLOGY (2015)
Intranasal Insulin Enhanced Resting-State Functional Connectivity of Hippocampal Regions in Type 2 Diabetes
Hui Zhang et al.
DIABETES (2015)
Central Nervous Insulin Administration Does Not Potentiate the Acute Glucoregulatory Impact of Concurrent Mild Hyperinsulinemia
Volker Ott et al.
DIABETES (2015)
Human apolipoprotein E ε4 expression impairs cerebral vascularization and blood-brain barrier function in mice
Wael Alata et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
Long-Acting Intranasal Insulin Detemir Improves Cognition for Adults with Mild Cognitive Impairment or Early-Stage Alzheimer's Disease Dementia
Amy Claxton et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies
Mark Yarchoan et al.
ACTA NEUROPATHOLOGICA (2014)
Insulin Regulates Brain Function, but How Does It Get There?
Sarah M. Gray et al.
DIABETES (2014)
Enhancement of Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
Vera Novak et al.
DIABETES CARE (2014)
Insulin induces phosphorylation of the AMPA receptor subunit GluR1, reversed by ZIP, and over-expression of Protein Kinase M zeta, reversed by amyloid beta
Linda Adzovic et al.
JOURNAL OF NEUROCHEMISTRY (2014)
GABAergic Neurogliaform Cells Represent Local Sources of Insulin in the Cerebral Cortex
Gabor Molnar et al.
JOURNAL OF NEUROSCIENCE (2014)
Neurobiology of food intake in health and disease
Gregory J. Morton et al.
NATURE REVIEWS NEUROSCIENCE (2014)
The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview
Per G. Djupesland et al.
THERAPEUTIC DELIVERY (2014)
Sex and ApoE Genotype Differences in Treatment Response to Two Doses of Intranasal Insulin in Adults with Mild Cognitive Impairment or Alzheimer's Disease
Amy Claxton et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Alzheimer's disease and insulin resistance: translating basic science into clinical applications
Fernanda G. De Felice
JOURNAL OF CLINICAL INVESTIGATION (2013)
Decay happens: the role of active forgetting in memory
Oliver Hardt et al.
TRENDS IN COGNITIVE SCIENCES (2013)
Elevated cerebrospinal fluid and blood concentrations of oxytocin following its intranasal administration in humans
Nadine Striepens et al.
SCIENTIFIC REPORTS (2013)
Glucose Intolerance, Insulin Resistance, and Pathological Features of Alzheimer Disease in the Baltimore Longitudinal Study of Aging
Madhav Thambisetty et al.
JAMA NEUROLOGY (2013)
Intranasal delivery of biologics to the central nervous system
Jeffrey J. Lochhead et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
Role of the blood-brain barrier in the evolution of feeding and cognition
William A. Banks
BRAIN AND OBESITY (2012)
Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment A Pilot Clinical Trial
Suzanne Craft et al.
ARCHIVES OF NEUROLOGY (2012)
Intranasal Insulin Suppresses Food Intake via Enhancement of Brain Energy Levels in Humans
Kamila Jauch-Chara et al.
DIABETES (2012)
Postprandial Administration of Intranasal Insulin Intensifies Satiety and Reduces Intake of Palatable Snacks in Women
Manfred Hallschmid et al.
DIABETES (2012)
Impaired Insulin Sensitivity as Indexed by the HOMA Score Is Associated With Deficits in Verbal Fluency and Temporal Lobe Gray Matter Volume in the Elderly
Christian Benedict et al.
DIABETES CARE (2012)
Poor Cognitive Function and Risk of Severe Hypoglycemia in Type 2 Diabetes Post hoc epidemiologic analysis of the ACCORD trial
Zubin Punthakee et al.
DIABETES CARE (2012)
Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism
V. Ott et al.
DIABETES OBESITY & METABOLISM (2012)
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
Konrad Talbot et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Anatomical and Histological Factors Affecting Intranasal Drug and Vaccine Delivery
Sveinbjorn Gizurarson
CURRENT DRUG DELIVERY (2012)
Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats
Claudia A. Grillo et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimer's Disease: Two Phase 3 Studies
C. Harrington et al.
CURRENT ALZHEIMER RESEARCH (2011)
Activity-Dependent Regulation of Surface Glucose Transporter-3
Jainne M. Ferreira et al.
JOURNAL OF NEUROSCIENCE (2011)
Olfactory Impairment in Older Adults: Five-Year Incidence and Risk Factors
Carla R. Schubert et al.
LARYNGOSCOPE (2011)
Metabolic syndrome and cognitive decline in French elders The Three-City Study
C. Raffaitin et al.
NEUROLOGY (2011)
Neuroendocrine responses to hypoglycemia
Nolawit Tesfaye et al.
YEAR IN DIABETES AND OBESITY (2010)
Euglycemic Infusion of Insulin Detemir Compared With Human Insulin Appears to Increase Direct Current Brain Potential Response and Reduces Food Intake While Inducing Similar Systemic Effects
Manfred Hallschmid et al.
DIABETES (2010)
Central Insulin Signaling Is Attenuated by Long-Term Insulin Exposure via Insulin Receptor Substrate-1 Serine Phosphorylation, Proteasomal Degradation, and Lysosomal Insulin Receptor Degradation
Christopher M. Mayer et al.
ENDOCRINOLOGY (2010)
Insulin Levels are Decreased in the Cerebrospinal Fluid of Women with Prodomal Alzheimer's Disease
Francisco J. Gil-Bea et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Comparable Sensitivity of Postmenopausal and Young Women to the Effects of Intranasal Insulin on Food Intake and Working Memory
Rosemarie Krug et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
Aileen M. Moloney et al.
NEUROBIOLOGY OF AGING (2010)
Insulin modulation of magnetoencephalographic resting state dynamics in lean and obese subjects
Krunoslav T. Stingl et al.
FRONTIERS IN SYSTEMS NEUROSCIENCE (2010)
The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia Two Roads Converged
Suzanne Craft
ARCHIVES OF NEUROLOGY (2009)
Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders?
M. Hallschmid et al.
DIABETOLOGIA (2009)
Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors
David R. Marks et al.
JOURNAL OF NEUROSCIENCE (2009)
Intranasal Drug Delivery: How, Why and What for?
Anaisa Pires et al.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2009)
Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease
L. Mosconi et al.
NEUROLOGY (2009)
Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers
Fernanda G. De Felice et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease
Lisa Mosconi et al.
MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)
Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease
Leah R. Hanson et al.
BMC NEUROSCIENCE (2008)
Cognitive dysfunction and diabetes mellitus
Christopher T. Kodl et al.
ENDOCRINE REVIEWS (2008)
Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair
Thomas. J. Nelson et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-β in memory-impaired older adults
Mark A. Reger et al.
JOURNAL OF ALZHEIMERS DISEASE (2008)
Differential sensitivity of men and women to anorexigenic and memory-improving effects of intranasal insulin
Christian Benedict et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo
Shu-Ling Chiu et al.
NEURON (2008)
Intranasal insulin attenuates the hypothalamic-pituitary-adrenal axis response to psychosocial stress
Andreas Bohringer et al.
PSYCHONEUROENDOCRINOLOGY (2008)
Intranasal insulin improves cognition and modulates β-amyloid in early AD
M. A. Reger et al.
NEUROLOGY (2008)
Obese men respond to cognitive but not to catabolic brain insulin signaling
M. Hallschmid et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans
O. Tschritter et al.
DIABETOLOGIA (2007)
Insulin expression in the brain and pituitary cells of tilapia (Oreochromis niloticus)
Olga Hrytsenko et al.
BRAIN RESEARCH (2007)
Intranasal insulin improves memory in humans: Superiority of insulin aspart
Christian Benedict et al.
NEUROPSYCHOPHARMACOLOGY (2007)
Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice
Lynda M. Brown et al.
PHYSIOLOGY & BEHAVIOR (2006)
Brain imaging in patients with diabetes - A systematic review
Barbera van Harten et al.
DIABETES CARE (2006)
Low cerebrospinal fluid insulin levels in obese humans
W. Kern et al.
DIABETOLOGIA (2006)
The cerebrocortical response to hyperinsulinemia is reduced in overweight humans:: A magnetoencephalographic study
Otto Tschritter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Gonadal hormones determine sensitivity to central leptin and insulin
DJ Clegg et al.
DIABETES (2006)
Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype
MA Reger et al.
NEUROBIOLOGY OF AGING (2006)
Effect of insulin on the brain activity obtained during visual and memory tasks in healthy human subjects
Luke Benedict et al.
NEUROENDOCRINOLOGY (2006)
Cognitive decline and dementia in diabetes - systematic overview of prospective observational studies
T Cukierman et al.
DIABETOLOGIA (2005)
Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-D-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner
LP van der Heide et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Insulin resistance: sex matters
B Mittendorfer
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2005)
Hypothalamic KATP channels control hepatic glucose production
A Pocai et al.
NATURE (2005)
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?
E Steen et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
Insulin affects the neuronal response in the medial temporal lobe in humans
M Rotte et al.
NEUROENDOCRINOLOGY (2005)
The source of cerebral insulin
WA Banks
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus
F Trudeau et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Insulin and neurodegenerative disease: shared and specific mechanisms
S Craft et al.
LANCET NEUROLOGY (2004)
Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain
M Hallschmid et al.
DIABETES (2004)
Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration
RG Thorne et al.
NEUROSCIENCE (2004)
Intranasal insulin improves memory in humans
C Benedict et al.
PSYCHONEUROENDOCRINOLOGY (2004)
Intranasal insulin reduces body fat in men but not in women
M Hallschmid et al.
DIABETES (2004)
ApoE genotype accounts for the vast majority of AD risk and AD pathology
J Raber et al.
NEUROBIOLOGY OF AGING (2004)
Intranasally administered insulin intended for prevention of type 1 diabetes -: a safety study in healthy adults
A Kupila et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2003)
Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: interactions with apolipoprotein E genotype
S Craft et al.
PSYCHONEUROENDOCRINOLOGY (2003)
Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly
A Convit et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Insulin and the blood-brain barrier
SC Woods et al.
CURRENT PHARMACEUTICAL DESIGN (2003)
The role of insulin in human brain glucose metabolism -: An 18fluoro-deoxyglucose positron emission tomography study
EM Bingham et al.
DIABETES (2002)
Cerebrospinal fluid levels of insulin in patients with Alzheimer's disease
JA Molina et al.
ACTA NEUROLOGICA SCANDINAVICA (2002)
Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes
EJ Rulifson et al.
SCIENCE (2002)
The effect of insulin on in vivo cerebral glucose concentrations and rates of glucose transport/metabolism in humans
ER Seaquist et al.
DIABETES (2001)
Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis
VA Skeberdis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Delivery of neurotrophic factors to the central nervous system - Pharmacokinetic considerations
RG Thorne et al.
CLINICAL PHARMACOKINETICS (2001)
The neurobiology of stress: from serendipity to clinical relevance
BS McEwen
BRAIN RESEARCH (2000)
Role of brain insulin receptor in control of body weight and reproduction
JC Brüning et al.
SCIENCE (2000)
Transport of drugs from the nasal cavity to the central nervous system
L Illum
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2000)
Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
P Kurtzhals et al.
DIABETES (2000)
Decreases in rat extracellular hippocampal glucose concentration associated with cognitive demand during a spatial task
EC McNay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
HY Man et al.
NEURON (2000)