4.5 Review

Elucidation of disease etiology by trans-layer omics analysis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

QTLbase: an integrative resource for quantitative trait loci across multiple human molecular phenotypes

Zhanye Zheng et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Multidisciplinary Sciences

Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

Anna S. E. Cuomo et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Expanded encyclopaedias of DNA elements in the human and mouse genomes

Jill E. Moore et al.

NATURE (2020)

Article Multidisciplinary Sciences

The GTEx Consortium atlas of genetic regulatory effects across human tissues

Francois Aguet et al.

SCIENCE (2020)

Review Immunology

Review: transcriptome and trans-omics analysis of systemic lupus erythematosus

Keishi Fujio et al.

INFLAMMATION AND REGENERATION (2020)

Article Genetics & Heredity

Opportunities and challenges for transcriptome-wide association studies

Michael Wainberg et al.

NATURE GENETICS (2019)

Article Genetics & Heredity

Probabilistic fine-mapping of transcriptome-wide association studies

Nicholas Mancuso et al.

NATURE GENETICS (2019)

Article Genetics & Heredity

NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements

Shigeki Hirabayashi et al.

NATURE GENETICS (2019)

Article Multidisciplinary Sciences

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

Apolline Gallois et al.

NATURE COMMUNICATIONS (2019)

Article Genetics & Heredity

Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs

Monique G. P. van der Wijst et al.

NATURE GENETICS (2018)

Review Urology & Nephrology

Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology

Anna Koettgen et al.

SEMINARS IN NEPHROLOGY (2018)

Article Multidisciplinary Sciences

Genomic atlas of the human plasma proteome

Benjamin B. Sun et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression

Benjamin J. Schmiedel et al.

Article Biochemistry & Molecular Biology

ChIP-Atlas: a data-mining suite powered by full integration of public ChIP-seq data

Shinya Oki et al.

EMBO REPORTS (2018)

Article Biochemistry & Molecular Biology

Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity

Saori Sakaue et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Multidisciplinary Sciences

Comprehensive functional genomic resource and integrative model for the human brain

Daifeng Wang et al.

SCIENCE (2018)

Article Biotechnology & Applied Microbiology

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

Emma E. Davenport et al.

GENOME BIOLOGY (2018)

Article Biotechnology & Applied Microbiology

A comprehensive map of molecular drug targets

Rita Santos et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Article Multidisciplinary Sciences

Genetic effects on gene expression across human tissues

Francois Aguet et al.

NATURE (2017)

Article Genetics & Heredity

Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis

Kazuyoshi Ishigaki et al.

NATURE GENETICS (2017)

Article Multidisciplinary Sciences

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Alexandra-Chloe Villani et al.

SCIENCE (2017)

Article Biochemistry & Molecular Biology

The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

Hendrik G. Stunnenberg et al.

Article Genetics & Heredity

Integrative approaches for large-scale transcriptome-wide association studies

Alexander Gusev et al.

NATURE GENETICS (2016)

Article Biochemistry & Molecular Biology

DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets

Felipe Albrecht et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Multidisciplinary Sciences

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

Johannes Kettunen et al.

NATURE COMMUNICATIONS (2016)

Article Biotechnology & Applied Microbiology

Systematic identification of genetic influences on methylation across the human life course

Tom R. Gaunt et al.

GENOME BIOLOGY (2016)

Article Multidisciplinary Sciences

Integrative analysis of 111 reference human epigenomes

Anshul Kundaje et al.

NATURE (2015)

Article Genetics & Heredity

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Brendan K. Bulik-Sullivan et al.

NATURE GENETICS (2015)

Article Genetics & Heredity

Cell Specific eQTL Analysis without Sorting Cells

Harm-Jan Westra et al.

PLOS GENETICS (2015)

Article Multidisciplinary Sciences

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Yukinori Okada et al.

NATURE (2014)

Article Multidisciplinary Sciences

A promoter-level mammalian expression atlas

Alistair R. R. Forrest et al.

NATURE (2014)

Article Genetics & Heredity

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

Lorenzo Pasquali et al.

NATURE GENETICS (2014)

Article Genetics & Heredity

An atlas of genetic influences on human blood metabolites

So-Youn Shin et al.

NATURE GENETICS (2014)

Article Multidisciplinary Sciences

Intersection of population variation and autoimmunity genetics in human T cell activation

Chun Jimmie Ye et al.

SCIENCE (2014)

Review Genetics & Heredity

Beyond GWASs: Illuminating the Dark Road from Association to Function

Stacey L. Edwards et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2013)

Review Genetics & Heredity

Mapping of Immune-Mediated Disease Genes

Isis Ricano-Ponce et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 14 (2013)

Review Immunology

Single-cell mass cytometry for analysis of immune system functional states

Zach B. Bjornson et al.

CURRENT OPINION IN IMMUNOLOGY (2013)

Article Biochemistry & Molecular Biology

Annotation of functional variation in personal genomes using RegulomeDB

Alan P. Boyle et al.

GENOME RESEARCH (2012)

Article Multidisciplinary Sciences

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham et al.

NATURE (2012)

Article Multidisciplinary Sciences

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

Matthew T. Maurano et al.

SCIENCE (2012)

Article Genetics & Heredity

A genome-wide association study of metabolic traits in human urine

Karsten Suhre et al.

NATURE GENETICS (2011)