期刊
FUTURE MEDICINAL CHEMISTRY
卷 9, 期 4, 页码 347-350出版社
FUTURE SCI LTD
DOI: 10.4155/fmc-2017-0009
关键词
E3 ligases; personalized medicine; protein-protein interactions; undruggable targets
资金
- Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat de Catalunya
- 7th European Framework Program-Marie Curie COFUND [600385]
- Spanish Ministerio de Economia y Competitividad [SAF2015-68749-R]
A balanced risk/gain assessment should be considered before starting a drug discovery project aiming to target E3 ligases and, crucially, the amount of k-nowledge for a given E3 ligase can foretell the chances of success.
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