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Recent advances in single-benzene-based fluorophores: physicochemical properties and applications

期刊

ORGANIC & BIOMOLECULAR CHEMISTRY
卷 19, 期 5, 页码 933-946

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ob02387f

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资金

  1. National Research Foundation (NRF) of Korea (Ministry of Science and ICT) [NRF-2019-M3A9H1103783]
  2. Bio & Medical Technology Development Program of the NRF of Korea (Ministry of Science ICT) [NRF-2018-M3A9H3021707]
  3. Basic Science Research Program through the NRF of Korea (Ministry of Education) [NRF-2018-R1A6A1A03025124, NRF-2018-R1D1A1B07043383]

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Fluorescence-based materials and techniques have been widely studied and applied in various fields, especially in biology and materials science. The development of organic molecule-based fluorophores has contributed to the advancement of research in this area. Recent studies have focused on single-benzene-based fluorophores (SBBFs), exploring their physicochemical properties and applications for the development of new derivatives in the field of fluorophore-related materials science.
Fluorescence-based materials and associated techniques (analytical, imaging, and sensing techniques) have been highlighted over the last century throughout various basic research fields and industries. Organic molecule-based fluorophores, in particular, have ushered in a new era in biology and materials science. To date, hundreds of organic fluorophores have been developed, and many studies have introduced new rationales for the fluorophore design and the analysis of the relationship between its structure and photophysical properties both in the solution- and solid-state. In this review, we summarize the recent advances (mainly from 2015 to 2020) in single-benzene-based fluorophores (SBBFs), which have an electron-donor (D)-acceptor (A) type dipolar structure within a compact benzene backbone. We also present a systematic outline of the physicochemical properties of SBBFs and representative examples of their applications, which will provide useful context for the development of new SBBF derivatives in fluorophore-related materials science fields.

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