期刊
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
卷 30, 期 1, 页码 229-232出版社
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1055-9965.EPI-20-1036
关键词
-
资金
- National Health and Medical Research Council (NHMRC) of Australia [GNT1025142, GNT1120431]
- NHMRC [GNT1073898, GNT1173346]
This study found that higher pre- and post-diagnosis diet quality was not associated with better survival outcomes in women with ovarian cancer. The research suggests that diet quality may not improve survival after a diagnosis of ovarian cancer.
Background: Prior studies evaluating diet quality in relation to ovarian cancer survival are sparse, and to date none have assessed diet quality or diet-quality change after diagnosis. Methods: In the prospective Ovarian cancer Prognosis And Life-style (OPAL) study, diet-quality scores were calculated using data from food frequency questionnaires completed pre-diagnosis (n = 650) and 12 months' post-diagnosis (n= 503). We used Cox proportional hazard models to estimate adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the association between diet quality and survival. Results: During the median follow-up of 4.4 years, 278 women died from ovarian cancer. There was no evidence of an association between diet quality pre- or post-diagnosis and progression-free, overall, or ovarian cancer-specific survival. No survival advantage was observed for women who had either improved their diet quality or who consumed a high-quality diet both before and 12 months after diagnosis. Conclusions: Higher pre- and post-diagnosis diet quality was not associated with better survival outcomes in this cohort of women with ovarian cancer. Impact: Diet quality is important for a range of health outcomes but may not improve survival after a diagnosis of ovarian cancer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据