4.6 Review

Promising drug targets and associated therapeutic interventions in Parkinson's disease

期刊

NEURAL REGENERATION RESEARCH
卷 16, 期 9, 页码 1730-1739

出版社

WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/1673-5374.306066

关键词

dopamine; epigenetics; gene therapies; glutamate receptor; levodopa; molecular chaperones; monoamine oxidase B; mucuna alpha-synuclein; Parkinson's disease; striatum; substantia nigra

资金

  1. UGC Dr. D.S. Kothari Postdoctoral Scheme [No-F.42/2006 (BSR)/BL/19-20/0032]

向作者/读者索取更多资源

Parkinson's disease is a debilitating brain disease with limited treatment options, highlighting the need for novel drug targets to improve patient health. Natural products may play a critical role in controlling the progression of Parkinson's disease.
Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious and etiological treatment is required. In this review, we have compiled the information covering limitations of current therapeutic options in PD, novel drug targets for PD, and finally, the role of some critical beneficial natural products to control the progression of PD.

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