Magnetic resonance thermometry using a GdIII-based contrast agent

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled.

Automated summary

The complexes described in this study act as contrast agents for magnetic resonance imaging thermometry, enhancing contrast between 275 and 325 K. The temperature response of the fluorinated contrast complex is primarily based on the modulation of water exchange caused by trifluoromethyl groups, which can be chemically controlled.