A Novel Photoprobe Based On Nano Tris(3-acetylindole)-terbium(III) Complex For The Quantitative Determination of Epinephrine In Blood Samples

A New photoprobe based on tris(3-acetylindole) terbium (III) complex (TbAcI) doped in polyethylene glycol (PEG) thin-film was synthesized, and employed as a novel, simple, sensitive, accurate, and precise method for the determination of Epinephrine (EPI) in different serum samples. The results obtained from the Stern-Volmer bimolecular quenching analysis was attributed to the presence of EPI in the surrounding of the emissive TbAcI. The calibration plot was prepared for the concentration range of 1-1500 pg/mL of EPI with a correlation coefficient of 0.99 and a detection limit of 0.1 pg/mL. That may aid in assessing the activity of the adrenal gland and then the diagnosis of optimal diseases that may be raised due to the abnormal ranges in human blood.

Automated summary

A new photoprobe based on TbAcI doped in PEG thin-film was synthesized for the determination of Epinephrine in serum samples. The method showed high sensitivity and accuracy, aiding in diagnosing diseases caused by abnormal blood ranges.