Organic-photoredox-catalyzed three-component sulfonylative pyridylation of styrenes

An efficient, metal-free protocol for the three-component sulfonylative pyridylation of styrenes via organic-photoredox catalysis is described. This metal-free process enables the direct and selective installation of sulfonyl and heteroaryl motifs and tolerates a wide array of functional groups as well as complex molecular scaffolds, that could complement previous methods and would be of interest in pharmaceutical research.

Automated summary

An efficient metal-free protocol for the three-component sulfonylative pyridylation of styrenes via organic-photoredox catalysis has been described. This process enables the direct and selective installation of sulfonyl and heteroaryl motifs, tolerating a wide range of functional groups and complex molecular scaffolds. It could complement previous methods and be of interest in pharmaceutical research.