期刊
CHEMICAL COMMUNICATIONS
卷 57, 期 15, 页码 1959-1962出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc07688k
关键词
-
资金
- National Natural Science Foundation of China [21961033]
This method utilizes a visible-light-mediated aerobic alpha-alkylation reaction of glycine derivatives with alkyl boronic acids in the presence of a Ru/Cu catalyst system to efficiently produce a wide range of complex unnatural alpha-amino-acid derivatives. It features mild reaction conditions and broad substrate scope.
A visible-light-mediated aerobic alpha-alkylation reaction of glycine derivatives with alkyl boronic acids has been established in the presence of a Ru/Cu catalyst system, giving the desired radical coupling products efficiently. The transformation features mild reaction conditions and broad substrate scope, delivering a wide range of complex unnatural alpha-amino-acid derivatives.
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