An enzyme cascade sensor with resistance to the inherent intermediate product by logic-controlled peroxidase mimic catalysis

Enzyme cascade sensors usually could not discriminate between the target and intermediate product. Herein, based on AND logic-controlled activation of the glucose oxidase-copper peroxide sensing system, enzyme cascade detection for glucose with resistance to inherently existing intermediate product H2O2 was reported for the first time, which may provide a novel way for facilitating enzyme cascade sensing.

Automated summary

The study introduces an enzyme cascade sensor based on AND logic that can differentiate between target and intermediate product, showing resistance to the inherently existing intermediate product H2O2, providing a new potential for enzyme cascade sensing.