B-Doped core-shell Fe@BC nanozymes: active site identification and bacterial inhibition

The rational design of nanozymes as new antibiotics for bacterial therapy is a promising area in healthcare. Herein, B-doped core-shell Fe@BC nanozymes functioned with peroxidase-like activity for bacterial inhibition were studied. Experimental and theoretical results show that the BCO2 site enables a much lower energy barrier than the BC2O site, with a positive correlation between the density and activity of BCO2. The enzyme-like and positively-charged properties of core-shell Fe@BC improve the production and utilization of OH to efficiently kill bacteria. This study not only highlights a promising peroxidase mimic for hygiene management but also deepens the understanding of B-doped carbon nanozymes.

Automated summary

The study focused on the peroxidase-like activity of B-doped core-shell Fe@BC nanozymes, finding that the BCO2 site has a lower activation energy barrier, with a positive correlation between density and activity. The enzyme-like and positively charged properties of the core-shell Fe@BC help improve the production and utilization of OH for efficiently killing bacteria.