The treatment of upper extremities deep vein thrombosis related to thoracic outlet syndrome with direct oral anticoagulants

Venous thoracic outlet syndrome (VTOS) is a manifestation of venous symptoms that occurs when the subclavian vein is compressed and it may present clinically with acute venous thrombosis of the axillo-subclavian vein. Evidence for the optimal approach to the management of this condition is sparse and actually anticoagulation alone is not considered an option. Herein we reported our experience with direct oral anticoagulants in patients with upper extremities deep vein thrombosis, due to VTOS, who refused endovascular approach or surgery.

Automated summary

Venous thoracic outlet syndrome (VTOS) can cause acute venous thrombosis when the subclavian vein is compressed, and there is limited evidence on the optimal management approach for this condition. Anticoagulation alone is not recommended for treatment in patients with upper extremities deep vein thrombosis due to VTOS who refuse endovascular approach or surgery.