4.8 Review

Stimuli-responsive nanobubbles for biomedical applications

期刊

CHEMICAL SOCIETY REVIEWS
卷 50, 期 9, 页码 5746-5776

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cs00839j

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资金

  1. National Natural Science Foundation of China [21774060, 21644004]
  2. European Research Council (ERC Consolidator Grant) [648124]
  3. Research Foundation Flanders (FWO) [1500418N, 12Q8718N]
  4. European Union's Horizon 2020 Research and Innovation Programme [810685]
  5. European Research Council (ERC) [648124] Funding Source: European Research Council (ERC)

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This review discusses the recent advances in stimuli-responsive nanobubbles for biomedical applications, highlighting their properties, synthesis methods, and potential advantages and limitations.
Stimuli-responsive nanobubbles have received increased attention for their application in spatial and temporal resolution of diagnostic techniques and therapies, particularly in multiple imaging methods, and they thus have significant potential for applications in the field of biomedicine. This review presents an overview of the recent advances in the development of stimuli-responsive nanobubbles and their novel applications. Properties of both internal- and external-stimuli responsive nanobubbles are highlighted and discussed considering the potential features required for biomedical applications. Furthermore, the methods used for synthesis and characterization of nanobubbles are outlined. Finally, novel biomedical applications are proposed alongside the advantages and shortcomings inherent to stimuli-responsive nanobubbles.

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