期刊
FRONTIERS IN NEUROENDOCRINOLOGY
卷 50, 期 -, 页码 67-90出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yfrne.2017.12.004
关键词
Stress; Depression; Immune function; Estrogen; Progesterone; Testosterone
资金
- Brain and Behavior Research foundation NARSAD Young Investigator award
Certain mood disorders and autoimmune diseases are predominately female diseases but we do not know why. Here, we explore the relationship between depression and the immune system from a sex-based perspective. This review characterizes sex differences in the immune system in health and disease. We explore the contribution of gonadal and stress hormones to immune function at the cellular and molecular level in the brain and body. We propose hormonal and genetic sex specific immune mechanisms that may contribute to the etiology of mood disorders.
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