Asymmetric [2+2] photocycloaddition via charge transfer complex for the synthesis of tricyclic chiral ethers

The asymmetric synthesis of chiral polycyclic ethers by an intramolecular [2+2] photocycloaddition is described. This process proceeded through a photocatalytically active iminium ion-based charge transfer (CT) complex under visible light irradiation. In this way a stereocontrolled [2+2] photocycloaddition is enabled leading to tricyclic products with good enantiomeric ratios.

Automated summary

The asymmetric synthesis of chiral polycyclic ethers is achieved through an intramolecular [2+2] photocycloaddition, utilizing a photocatalytically active iminium ion-based charge transfer complex under visible light irradiation. This method enables stereocontrolled [2+2] photocycloaddition, yielding tricyclic products with good enantiomeric ratios.