期刊
CURRENT ONCOLOGY
卷 28, 期 1, 页码 693-701出版社
MDPI
DOI: 10.3390/curroncol28010068
关键词
esophageal cancer; minimally invasive esophagectomy; open esophagectomy; quality of life; KPS; QLQC-30; OES-18
类别
资金
- Major medical scientific research subject of Hebei province [zd2013044]
- Medical application tracking project of Hebei province [GL201637]
- Science and Technique project of Health Commission of Hebei Province for Young Scientists [20180573]
The study demonstrates that minimally invasive esophagectomy offers a better short-term quality of life for patients with resectable esophageal cancer compared to open esophagectomy. The MIE group showed higher one-year survival rate, less intraoperative bleeding and lower incidence of postoperative pneumonia than the OE group. Additionally, the MIE group had significantly better Karnofshy performance scale (KPS), QLQC-30 score and OES-18 score at various time points after surgery compared to the OE group. Overall, the short-term quality of life was better in the MIE group.
This study investigates whether minimally invasive esophagectomy (MIE) is a safe and effective way for patients with resectable esophageal cancer by comparing the short-term quality of life (QOL) after minimally invasive esophagectomy and open esophagectomy (OE). A total number of 104 patients who underwent esophagectomy from January 2013 to March 2014 were enrolled in this study. These patients were divided into two groups (MIE and OE group). Three scoring scales of quality of life were used to evaluate QOL before the operation and at the first, third, sixth and twelfth months after MIE or OE, which consist of Karnofshy performance scale (KPS), the European Organization for Research and Treatment questionnaire QLQC-30 (EORTC QLQC-30) and esophageal cancer supplement scale (OES-18). The MIE group was higher than the OE group in one-year survival rate (92.54% vs. 72.00%). Significant differences between the two groups were observed in intraoperative bleeding volume (158.53 +/- 91.07 mL vs. 228.97 +/- 109.33 mL, p = 0.001), and the incidence of postoperative pneumonia (33.33% vs. 58.62%, p = 0.018). The KPS of MIE group was significantly higher than the OE group at the first (80 vs. 70, p = 0.004 < 0.05), third (90 vs. 80, p = 0.006 < 0.05), sixth (90 vs. 80, p = 0.007 < 0.05) and twelfth months (90 vs. 80, p = 0.004 < 0.05) after surgery. The QLQC-30 score of MIE group was better than OE group at first and twelfth months after the operation. The OES-18 score of MIE group was significantly better than OE group at first, sixth and twelfth months after surgery. The short-term quality of life in MIE group was better than OE group.
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