Metatranscriptomic Analysis Reveals SARS-CoV-2 Mutations in Wastewater of the Frankfurt Metropolitan Area in Southern Germany

Article Infectious Diseases

SARS Coronavirus-2 variant tracing within the first Coronavirus Disease 19 clusters in northern Germany

Susanne Pfefferle et al.

Summary: By analyzing the respiratory samples from SARS-CoV-2 infected patients in early infection clusters in Hamburg, it was possible to identify infection clusters, track transmission chains, and study the evolution of virus variants. The study highlights the importance of detailed virus variant analysis in understanding the spread of infections and tracking viral evolution.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

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Editorial Material Infectious Diseases

Updated rapid risk assessment from ECDC on the risk related to the spread of new SARS-CoV-2 variants of concern in the EU/EEA - first update

EUROSURVEILLANCE (2021)

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Letter Medicine, General & Internal

An action plan for pan-European defence against new SARS-CoV-2 variants

Viola Priesemann et al.

LANCET (2021)

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Article Microbiology

Genome Sequencing of Sewage Detects Regionally Prevalent SARS-CoV-2 Variants

Alexander Crits-Christoph et al.

Summary: Viral genome sequencing, including from wastewater, provides valuable insights into the spread and genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. By analyzing sewage samples, researchers can track specific viral strains and potential introductions of new lineages before they are identified through clinical sequencing.

MBIO (2021)

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Article Public, Environmental & Occupational Health

Emergence of SARS-CoV-2 B.1.1.7 Lineage — United States, December 29, 2020–January 12, 2021

Summer E. Galloway et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Multidisciplinary Sciences

Long-term monitoring of SARS-CoV-2 RNA in wastewater of the Frankfurt metropolitan area in Southern Germany

Shelesh Agrawal et al.

Summary: Wastewater-based epidemiology is an effective method to monitor the scale and dynamics of infections in a city, with the SARS-CoV-2 RNA concentration in raw sewage in the Frankfurt metropolitan area showing a resurgence in August. This suggests a continuous increase in COVID-19 cases in Frankfurt.

SCIENTIFIC REPORTS (2021)

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Article Biology

COVID-19 CG enables SARS-CoV-2 mutation and lineage tracking by locations and dates of interest

Albert Tian Chen et al.

Summary: COVID-19 CG is an open resource for tracking SARS-CoV-2 single-nucleotide variations, lineages, and clades using the GISAID database. Users can query SNVs across different regions, mutations impacting diagnostic sensitivity, and the emergence of dominant lineages. The platform will be upgraded with new features to rapidly pinpoint mutations as the virus evolves and in response to interventions.

ELIFE (2021)

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Article Virology