期刊
THORAX
卷 76, 期 4, 页码 396-398出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/thoraxjnl-2020-215818
关键词
viral infection; respiratory infection
资金
- Department of Health NIHR Biomedical Research Centre funding scheme
- Wellcome Trust Clinical Research Career Development Fellowship [209553/Z/17/Z]
- MRC [MR/N007727/1] Funding Source: UKRI
Following discharge from hospital, a significant number of COVID-19 patients continue to experience persistent symptoms such as breathlessness, cough, fatigue, and depression. Some patients also show elevated levels of biomarkers indicating ongoing health issues. Chest radiographs reveal abnormalities in a considerable portion of patients, with a small percentage showing deterioration.
Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough and 69% fatigue. 14.6% had depression. In those discharged with elevated biomarkers, 30.1% and 9.5% had persistently elevated d-dimer and C reactive protein, respectively. 38% of chest radiographs remained abnormal with 9% deteriorating. Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.
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