Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples

Article Immunology

Mass Screening of Asymptomatic Persons for Severe Acute Respiratory Syndrome Coronavirus 2 Using Saliva

Isao Yokota et al.

Summary: This mass screening study showed that both NPS and saliva specimens had high sensitivity and specificity, with self-collected saliva specimens being valuable for detecting SARS-CoV-2 in mass screening of asymptomatic individuals. Viral load was highly correlated between NPS and saliva specimens in individuals testing positive.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Virology

Saliva sample pooling for the detection of SARS-CoV-2

Ekawat Pasomsub et al.

Summary: Saliva has been found to be a potential alternative specimen for detecting SARS-CoV-2, and pooling saliva samples for testing can help conserve healthcare resources without compromising the detection of the virus.

JOURNAL OF MEDICAL VIROLOGY (2021)

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Article Multidisciplinary Sciences

Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening

Daniel B. Larremore et al.

Summary: The COVID-19 pandemic has led to a public health crisis due to the spread of SARS-CoV-2 through presymptomatic, symptomatic, and asymptomatic individuals. Effective population screening for the virus is essential for reopening societies and controlling its spread, with testing frequency and reporting speed playing crucial roles in its success. Test sensitivity is only marginally important compared to these factors.

SCIENCE ADVANCES (2021)

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Article Pathology