期刊
FORENSIC SCIENCE MEDICINE AND PATHOLOGY
卷 13, 期 1, 页码 58-66出版社
HUMANA PRESS INC
DOI: 10.1007/s12024-016-9821-x
关键词
Autopsy; Perinatal; Imaging; Forensic; Pediatric; MRI
资金
- NIHR Clinician Scientist Fellowship award
- NIHR Senior Investigator award
- Great Ormond Street Children's Charity
- NIHR Great Ormond Street Hospital Biomedical Research Centre
- National Institute for Health Research (NIHR)
- Great Ormond Street Hospital Biomedical Research Centre
- Great Ormond Street Hospital Childrens Charity [V0117] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0513-10046, NIHR-CS-012-002] Funding Source: researchfish
Perinatal autopsy practice is undergoing a state of change with the introduction of evidence-based cross-sectional imaging, driven primarily by parental choice. In particular, the introduction of post mortem magnetic resonance imaging (PMMR) has helped to advance less-invasive perinatal autopsy in the United Kingdom (UK) and Europe. However, there are limitations to PMMR and other imaging techniques which need to be overcome, particularly with regard to imaging very small fetuses. Imaging is also now increasingly used to investigate particular deaths in childhood, such as suspected non-accidental injury (NAI) and sudden unexpected death in infancy (SUDI). Here we focus on current topical developments the field, with particular emphasis on the application of imaging to perinatal autopsy, and pediatric forensic deaths. Different imaging modalities and their relative advantages and disadvantages are discussed, together with other benefits of more advanced cross-sectional imaging which currently lie in the research domain. Whilst variations in local imaging service provision and need may determine different practice patterns, and access to machines and professionals with appropriate expertise and experience to correctly interpret the findings may limit current practices, we propose that gold standard perinatal and pediatric autopsy services would include complete PMMR imaging prior to autopsy, with PMCT in suspicious childhood deaths. This approach would provide maximal diagnostic yield to the pathologist, forensic investigator and most importantly, the parents.
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