An organophosphorus-mediated cross-Rauhut-Currier/Wittig domino reaction for the efficient synthesis of trisubstituted cyclopentenes

An efficient organophosphorus-mediated cross-Rauhut-Currier/Wittig domino reaction of vinyl ketones with chalcones has been developed for the synthesis of trisubstituted cyclopentenes. The new synthetic method has the advantages of mild reaction conditions, high efficiency, environmental friendliness and satisfactory yields.

Automated summary

An efficient organophosphorus-mediated cross-Rauhut-Currier/Wittig domino reaction has been developed for the synthesis of trisubstituted cyclopentenes, showing advantages of mild reaction conditions, high efficiency, environmental friendliness, and satisfactory yields.