4.7 Article

Dasatinib self-assembled nanoparticles decorated with hyaluronic acid for targeted treatment of tumors to overcome multidrug resistance

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Emodin regulates cell cycle of non-small lung cancer (NSCLC) cells through hyaluronan synthase 2 (HA2)-HA-CD44/receptor for hyaluronic acid-mediated motility (RHAMM) interaction-dependent signaling pathway

Mingzhu Li et al.

Summary: This study demonstrates that emodin regulates the cell cycle of NSCLC cells through the HAS2-HA-CD44/RHAMM interaction-dependent signaling pathway.

CANCER CELL INTERNATIONAL (2021)

Article Chemistry, Applied

pH-sensitive chitosan nanoparticles loaded with dolutegravir as milk and food admixture for paediatric anti-HIV therapy

K. Priya Dharshini et al.

Summary: The study aimed to develop Chitosan-based polymeric nanoparticles of anti-HIV drug Dolutegravir, which showed improved therapeutic efficiency and lesser cytotoxicity compared to the pure drug in treating HIV-infected T-lymphatic cell lines. The use of Chitosan from a novel source for drug delivery carrier has opened exceptional prospects for delivering drugs efficiently to paediatrics.

CARBOHYDRATE POLYMERS (2021)

Article Engineering, Biomedical

An injectable hydrogel using an immunomodulating gelator for amplified tumor immunotherapy by blocking the arginase pathway

Xiaomeng Ren et al.

Summary: An injectable hydrogel strategy was developed using an L-norvaline-based immunomodulating gelator to effectively block the ARG1 pathway and enhance immunotherapeutic efficacy. The designed hydrogel ensured high drug loading and controlled release of L-norvaline, addressing previous issues with burst release. The combination with doxorubicin hydrochloride demonstrated potent immunotherapy for tumor removal and metastasis inhibition.

ACTA BIOMATERIALIA (2021)

Article Chemistry, Physical

Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy

Hailong Tian et al.

Summary: The study developed a novel Cu-MOF-199 nanoplatform integrating vitamin K3, which modulates endogenous H2O2 and GSH levels to amplify the effect of chemodynamic therapy, effectively inhibiting tumor growth with minimal side effects in vivo.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

Article Chemistry, Multidisciplinary

A two-pronged photodynamic nanodrug to prevent metastasis of basal-like breast cancer

Jing Zhang et al.

Summary: The study proposed a two-pronged concept combining photodynamic therapy and epithelial-mesenchymal transition blockade to combat basal-like breast cancer metastasis. Ce6/Epa nanoparticles effectively prevented BLBC metastasis in vivo, offering a promising dual strategy against BLBC metastasis.

CHEMICAL COMMUNICATIONS (2021)

Article Chemistry, Physical

Engineering a photosensitizer nanoplatform for amplified photodynamic immunotherapy via tumor microenvironment modulation

Yaxin Zhou et al.

Summary: The engineered photosensitizer nanoplatform integrates chlorin e6, axitinib, and dextro-1-methyl tryptophan to enhance the efficacy of photodynamic immunotherapy by modulating the tumor microenvironment. This approach improves PDT and immunotherapy effects by normalizing tumor blood vessels and inhibiting IDO activity.

NANOSCALE HORIZONS (2021)

Review Pharmacology & Pharmacy

Clinical Pharmacokinetics and Pharmacodynamics of Dasatinib

Dominique Leveque et al.

CLINICAL PHARMACOKINETICS (2020)

Article Materials Science, Biomaterials

Active-targeting and acid-sensitive pluronic prodrug micelles for efficiently overcoming MDR in breast cancer

Cheng Xu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Article Pharmacology & Pharmacy

CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment

A. Tirella et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Article Nanoscience & Nanotechnology

Tumor-targeted drug delivery and sensitization by MMP2-responsive polymeric micelles

Qing Yao et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)

Article Pharmacology & Pharmacy

Verapamil delivery systems on the basis of mesoporous ZSM-5/KIT-6 and ZSM-5/SBA-15 polymer nanocomposites as a potential tool to overcome MDR in cancer cells

Margarita Popova et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Article Nanoscience & Nanotechnology

Co-Delivery of Docetaxel and Salinomycin to Target Both Breast Cancer Cells and Stem Cells by PLGA/TPGS Nanoparticles

Jie Gao et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Materials Science, Biomaterials

Preparation and in vitro evaluation of radiolabeled HA-PLGA nanoparticles as novel MTX delivery system for local treatment of rheumatoid arthritis

R. Maydelid Trujillo-Nolasco et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Biochemistry & Molecular Biology

Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer

Evgenia Karousou et al.

MATRIX BIOLOGY (2017)

Review Pharmacology & Pharmacy

MDR in cancer: Addressing the underlying cellular alterations with the use of nanocarriers

Manu S. Singh et al.

PHARMACOLOGICAL RESEARCH (2017)

Article Medicine, Research & Experimental

Folic Acid-Targeted Etoposide Cubosomes for Theranostic Application of Cancer Cell Imaging and Therapy

Yong Tian et al.

MEDICAL SCIENCE MONITOR (2017)

Article Medicine, Research & Experimental

CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches

Karin Williams et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2013)

Article Multidisciplinary Sciences

Kinetics of MDR Transport in Tumor-Initiating Cells

Vasilij Koshkin et al.

PLOS ONE (2013)

Review Oncology

Multidrug resistance in cancer: Role of ATP-dependent transporters

MM Gottesman et al.

NATURE REVIEWS CANCER (2002)