期刊
FOOD RESEARCH INTERNATIONAL
卷 91, 期 -, 页码 92-102出版社
ELSEVIER
DOI: 10.1016/j.foodres.2016.11.034
关键词
Wheat breeding; Coeliac disease; Gluten peptides; In vitro digestion; Old wheat
资金
- Emilia Romagna Region [LR 28/98, 49, LR28/98]
Coeliac disease is an autoimmune enteropathy that develops in genetically predisposed subjects after the ingestion of gluten or related proteins. Coeliac disease has an increasing incidence in the last years in western countries and it has been suggested that wheat breeding might have contributed to select more toxic forms of gluten. In this work, we analysed gluten peptides generated by in vitro digestion of different old and modern Triticum varieties, using LC-MS. We concluded that old varieties analysed produced a higher quantity of peptides containing immunogenic and toxic sequences than modern ones. Thus old wheat lines are not to be considered safer for subjects that are genetically predisposed to celiac disease. (C) 2016 Elsevier Ltd. All rights reserved.
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