期刊
STROKE AND VASCULAR NEUROLOGY
卷 6, 期 1, 页码 121-127出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/svn-2020-000408
关键词
MRI; brain; technique
资金
- National Science Foundation of China [81801199, 81830038, 81971094, 91949208]
- Beijing Municipal Science & Technology Commission [Z181100001818001]
Stem cells have strong proliferation and differentiation abilities, transplantation of which is important for treating neurological diseases, and tracking technologies help monitor the survival and distribution of transplanted cells.
Stem cells (SCs) are cells with strong proliferation ability, multilineage differentiation potential and self-renewal capacity. SC transplantation represents an important therapeutic advancement for the treatment strategy of neurological diseases, both in the preclinical experimental and clinical settings. Innovative and breakthrough SC labelling and tracking technologies are widely used to monitor the distribution and viability of transplanted cells non-invasively and longitudinally. Here we summarised the research progress of the main tracers, labelling methods and imaging technologies involved in current SC tracking technologies for various neurological diseases. Finally, the applications, challenges and unresolved problems of current SC tracing technologies were discussed.
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