4.2 Review

Genomics and functional genomics in Leishmania and Trypanosoma cruzi: statuses, challenges and perspectives

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Microbiology

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

Wei Wang et al.

Summary: The protozoan Trypanosoma cruzi establishes life-long infections in humans and other mammals due to the genetic diversity in genes encoding target antigens, which allows the parasite to evade immune responses. This diversity is maintained through processes like gene amplification and recombination, leading to extreme genome flexibility. This poses challenges for developing protective vaccines and contributes to the species-specific biological diversity of T. cruzi.

PLOS PATHOGENS (2021)

Article Biochemical Research Methods

Hap10: reconstructing accurate and long polyploid haplotypes using linked reads

Sina Majidian et al.

BMC BIOINFORMATICS (2020)

Article Biotechnology & Applied Microbiology

ComHapDet: a spatial community detection algorithm for haplotype assembly

Abishek Sankararaman et al.

BMC GENOMICS (2020)

Review Infectious Diseases

Trypanosoma cruziGenome 15 Years Later: What Has Been Accomplished?

Jose Luis Ramirez

TROPICAL MEDICINE AND INFECTIOUS DISEASE (2020)

Article Evolutionary Biology

Nanopore Sequencing Significantly Improves Genome Assembly of the Protozoan Parasite Trypanosoma cruzi

Florencia Diaz-Viraque et al.

GENOME BIOLOGY AND EVOLUTION (2019)

Article Multidisciplinary Sciences

Meiotic sex in Chagas disease parasite Trypanosoma cruzi

Philipp Schwabl et al.

NATURE COMMUNICATIONS (2019)

Article Parasitology

Assessment of two CRISPR-Cas9 genome editing protocols for rapid generation of Trypanosoma cruzi gene knockout mutants

Gabriela Assis Burle-Caldas et al.

INTERNATIONAL JOURNAL FOR PARASITOLOGY (2018)

Article Multidisciplinary Sciences

Genomic assemblies of newly sequenced Trypanosoma cruzi strains reveal new genomic expansion and greater complexity

Francisco Callejas-Hernandez et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

A CRISPR Cas9 high-throughput genome editing toolkit for kinetoplastids

Tom Beneke et al.

ROYAL SOCIETY OPEN SCIENCE (2017)

Article Ecology

Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani

Pablo Prieto Barja et al.

NATURE ECOLOGY & EVOLUTION (2017)

Article Biotechnology & Applied Microbiology

Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains

Joao Luis Reis-Cunha et al.

BMC GENOMICS (2015)

Article Cell Biology

First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites

Lauriane Sollelis et al.

CELLULAR MICROBIOLOGY (2015)

Review Biochemistry & Molecular Biology

Expanding the tool box for genetic manipulation of Trypanosoma cruzi

Gabriela de Assis Burle-Caldas et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2015)

Article Biochemistry & Molecular Biology

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

Matthew B. Rogers et al.

GENOME RESEARCH (2011)

Article Infectious Diseases

Phylogeography and Taxonomy of Trypanosoma brucei

Oliver Balmer et al.

PLOS NEGLECTED TROPICAL DISEASES (2011)

Article Infectious Diseases

Recent, Independent and Anthropogenic Origins of Trypanosoma cruzi Hybrids

Michael D. Lewis et al.

PLOS NEGLECTED TROPICAL DISEASES (2011)

Article Biotechnology & Applied Microbiology

Chromosome level assembly of the hybrid Trypanosoma cruzi genome

D. Brent Weatherly et al.

BMC GENOMICS (2009)

Article Multidisciplinary Sciences

Demonstration of Genetic Exchange During Cyclical Development of Leishmania in the Sand Fly Vector

Natalia S. Akopyants et al.

SCIENCE (2009)

Article Genetics & Heredity

Comparative genomic analysis of three Leishmania species that cause diverse human disease

Christopher S. Peacock et al.

NATURE GENETICS (2007)

Review Microbiology

Trypanosoma cruzi surface mucins:: host-dependent coat diversity

CA Buscaglia et al.

NATURE REVIEWS MICROBIOLOGY (2006)

Article Multidisciplinary Sciences

Comparative genomics of trypanosomatid parasitic protozoa

NM El-Sayed et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

NM El-Sayed et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

The genome of the kinetoplastid parasite, Leishmania major

AC Ivens et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

The genome of the African trypanosome Trypanosoma brucei

M Berriman et al.

SCIENCE (2005)

Article Biochemistry & Molecular Biology

Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi

WD DaRocha et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2004)