期刊
ORGANIC COMMUNICATIONS
卷 14, 期 1, 页码 81-91出版社
ACG PUBLICATIONS
DOI: 10.25135/acg.oc.99.21.01.1948
关键词
one-pot reaction; green chemistry; solvent-free; Knoevenagel condensation reaction; malononitrile; room temperature
资金
- UGC [UGC-MRP:F.43-181/2014(SR)]
- VGST, Govt. of Karnataka
- Department of Science and Technology
This paper presents a novel Knoevenagel reaction protocol using agro-waste extracts as catalyst, which efficiently reacts various substituted aromatic and heterocyclic aldehydes. The method also allows for direct isolation of the formed products with good yields.
This paper present a novel Knoevenagel reaction protocol for the condensation of aromatic/heteroaromatic aldehydes with malononitrile to give alpha, beta-unsaturated benzylidene derivatives. The main focus of this work is to reveal the usability of agro-waste extracts as a catalyst in the Knoevenagel condensation. The present protocol proceeds efficiently for various substituted aromatic and heterocyclic aldehydes in the Knoevenagel reactions. In addition, the present method describes direct isolation of the formed products without using organic solvent extraction gave good yields product. (C) 2021 ACG Publication. All right reserved.
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