期刊
INDIAN JOURNAL OF OPHTHALMOLOGY
卷 69, 期 4, 页码 932-936出版社
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/ijo.IJO_1558_20
关键词
Etiology; infantile cataract; pediatric cataract surgery; rubella cataract; TORCH
资金
- Hyderabad Eye Research Foundation (HERF)
This study investigated the etiology, clinical presentation, and morphology of congenital cataracts in a tertiary care center, identifying familial cataracts and those possibly due to TORCH infections as the predominant causes. Some patients also had congenital heart defects.
Purpose: To report the etiology, clinical presentation, and morphology of congenital cataract in a tertiary care center. Methods: It is a prospective cohort study conducted at L V Prasad Eye Institute, Hyderabad. All children with congenital cataract <= 12 months of age that required surgical intervention between August 2015 and July 2016 were included in the study. 109 such patients were subjected to meticulous history taking, pedigree charting, ocular, and systemic examination, B-scan, TORCH testing, clinical photographs, pediatrician consult and blood tests, which included serum calcium, serum phosphorous and urine for reducing sugars. Results: The mean age of presentation was 4.1 months (+/- 2.6 months) and both the genders were equally affected (P = 0.49). Eighty-five patients (77.9%) presented with bilateral cataracts while 24 patients had a unilateral presentation ( 22.1%). The common morphological presentation was either a total or a nuclear cataract, both variants noticed in 47 patients (43.1%). TORCH infections were responsible for a maximum (37 patients, 33.4%) number of cases followed by familial (20 patients, 18%) and developmental anomalies (11 patients, 10.1%) while the total number of idiopathic cases were 24% (27 patients). Eighteen patients (16.5%) had congenital heart defects and the majority (16 patients, 88.9%) of these had positive TORCH titres. Conclusion: Familial cataract and those possibly due to TORCH are still the predominant cause of congenital cataract in this series-highlighting the role of vaccination and preventive measures.
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