Sleep Disorders in Stroke: An Update on Management

Stroke is a leading cause of disability and mortality all over the world. Due to an aging population, the incidence of stroke is rising significantly, which has led to devastating consequences for patients. In addition to traditional risk factors such as age, hypertension, hyperlipidemia, diabetes and atrial fibrillation, sleep disorders, as independent modifiable risk factors for stroke, have been highlighted increasingly. In this review, we provide an overview of common types of current sleep disturbances in cerebrovascular diseases, including insomnia, hypersomnia, breathing-related sleep disorders, and parasomnias. Moreover, evidence-based clinical therapeutic strategies and pitfalls of specific sleep disorders after stroke are discussed. We also review the neurobiological mechanisms of these treatments as well as their effects on stroke. Since depression after stroke is so prevalent and closely related to sleep disorders, treatments of post-stroke depression are also briefly mentioned in this review article.

Automated summary

Stroke is a major cause of disability and mortality worldwide, with increasing incidence due to aging population. In addition to traditional risk factors, sleep disorders are being highlighted as independent modifiable risk factors for stroke. This review provides an overview of common types of sleep disturbances in cerebrovascular diseases and discusses evidence-based clinical therapeutic strategies and neurobiological mechanisms of treatments for specific sleep disorders after stroke.