相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease
Raymond S. Turner et al.
ANNALS OF NEUROLOGY (2020)
The Mitochondrial Protein VDAC1 at the Crossroads of Cancer Cell Metabolism: The Epigenetic Link
Zohar Amsalem et al.
CANCERS (2020)
Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer's Mice
Jelena Djordjevic et al.
CELLS (2020)
Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders?
Jack van Horssen et al.
NEUROSCIENCE LETTERS (2019)
Drp1/Fis1-mediated mitochondrial fragmentation leads to lysosomal dysfunction in cardiac models of Huntington's disease
A. U. Joshi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2019)
Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity
Maria S. Ioannou et al.
CELL (2019)
RelB controls adaptive responses of astrocytes during sterile inflammation
Angela S. Gupta et al.
GLIA (2019)
A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain
Gyun Jee Song et al.
FRONTIERS IN PHARMACOLOGY (2019)
Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways
Artem P. Gureev et al.
FRONTIERS IN GENETICS (2019)
Regional hypometabolism in the 3xTg mouse model of Alzheimer's disease
Aida Adlimoghaddam et al.
NEUROBIOLOGY OF DISEASE (2019)
Cellular Specificity of NF-κB Function in the Nervous System
Erica C. Dresselhaus et al.
FRONTIERS IN IMMUNOLOGY (2019)
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Caroline Fecher et al.
NATURE NEUROSCIENCE (2019)
Dynamics of Dynamin-Related Protein 1 in Alzheimer's Disease and Other Neurodegenerative Diseases
Darryll Oliver et al.
CELLS (2019)
What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion?
Benedict C. Albensi
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
Astrocytes and microglia: Models and tools
Kevin A. Guttenplan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Activation of mitochondrial fusion provides a new treatment for mitochondria-related diseases
Aliz Szabo et al.
BIOCHEMICAL PHARMACOLOGY (2018)
The tyrosine kinase inhibitor nilotinib is more efficient than mitotane in decreasing cell viability in spheroids prepared from adrenocortical carcinoma cells
Elaine Silveira et al.
CANCER CELL INTERNATIONAL (2018)
Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy
Marc Fakhoury
CURRENT NEUROPHARMACOLOGY (2018)
Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency
Guilhian Leipnitz et al.
SCIENTIFIC REPORTS (2018)
Cell Death Is Counteracted by Mitophagy in HIV-Productively Infected Astrocytes but Is Promoted by Inflammasome Activation Among Non-productively Infected Cells
Diego S. Ojeda et al.
FRONTIERS IN IMMUNOLOGY (2018)
Mitochondrial metabolism and cancer
Paolo Ettore Porporato et al.
CELL RESEARCH (2018)
Chronic dietary creatine enhances hippocampal-dependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-kappa B
Wanda M. Snow et al.
LEARNING & MEMORY (2018)
Mitochondria as a target for neuroprotection: implications for Alzheimer's disease
Susana Cardoso et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2017)
Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs
Jose Iglesias et al.
MOLECULAR NEUROBIOLOGY (2017)
Mitochondria as a target for neuroprotection: implications for Alzheimer's disease
Susana Cardoso et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2017)
Mitochondria-Division Inhibitor 1 Protects Against Amyloid-beta induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease
P. Hemachandra Reddy et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System
Vivek Lawana et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival
Jordan Rose et al.
TOXICOLOGY (2017)
Microglial M1/M2 polarization and metabolic states
Ruben Orihuela et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
NF-kappa B pathway controls mitochondrial dynamics
M. Laforge et al.
CELL DEATH AND DIFFERENTIATION (2016)
Mechanisms of Mitochondrial Dysfunction in Alzheimer's Disease
Chris Cadonic et al.
MOLECULAR NEUROBIOLOGY (2016)
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
Zhenyu Zhong et al.
CELL (2016)
Role of mitochondrial dysfunction in cancer progression
Chia-Chi Hsu et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2016)
Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway
Lauren J. Simmons et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Nilotinib reduced the viability of human ovarian cancer cells via mitochondria-dependent apoptosis, independent of JNK activation
Tze-Chien Chen et al.
TOXICOLOGY IN VITRO (2016)
Nilotinib Effects in Parkinson's Disease and Dementia with Lewy Bodies
Fernando Pagan et al.
JOURNAL OF PARKINSONS DISEASE (2016)
Transcriptional Control of Synaptic Plasticity by Transcription Factor NF-κB
Christian Engelmann et al.
NEURAL PLASTICITY (2016)
Ammonia as a Potential Neurotoxic Factor in Alzheimer's Disease
Aida Adlimoghaddam et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)
The association between PGC-1α and Alzheimer's disease
Gary Sweeney et al.
ANATOMY & CELL BIOLOGY (2016)
Mitochondrial fusion provides an 'initial metabolic complementation' controlled by mtDNA
Liang Yang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer's Disease
Hong Lian et al.
NEURON (2015)
Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease
Fabian A. Cabezas-Opazo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Astrocytic metabolic and inflammatory changes as a function of age
Tianyi Jiang et al.
AGING CELL (2014)
The role of reciprocal activation of cAbl and Mst1 in the Oxidative death of cultured astrocytes
Sook-Jeong Lee et al.
GLIA (2014)
Neuroinflammation in Alzheimer's disease: an understanding of physiology and pathology
M. Obulesu et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2014)
Inhibitors of Mitochondrial Fission as a Therapeutic Strategy for Diseases with Oxidative Stress and Mitochondrial Dysfunction
P. Hemachandra Reddy
JOURNAL OF ALZHEIMERS DISEASE (2014)
Intromitochondrial IκB/NF-κB signaling pathway is involved in amyloid β peptide-induced mitochondrial dysfunction
Chun Shi et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2014)
Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance
Irina Lonskaya et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2014)
Synaptic NF-kappa B pathway in neuronal plasticity and memory
Angeles Salles et al.
JOURNAL OF PHYSIOLOGY-PARIS (2014)
Apoptosis in Alzheimer's Disease: An Understanding of the Physiology, Pathology and Therapeutic Avenues
M. Obulesu et al.
NEUROCHEMICAL RESEARCH (2014)
Nilotinib in Combination with Carboplatin and Paclitaxel Is a Candidate for Ovarian Cancer Treatment
Marion T. Weigel et al.
ONCOLOGY (2014)
Mitochondrial dysfunction in cancer
Kinga Ksiezakowska-Lakoma et al.
MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY (2014)
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
Phillip M. Rappold et al.
NATURE COMMUNICATIONS (2014)
Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance
Michaeline L. Hebron et al.
AUTOPHAGY (2013)
The Kunitz-protease inhibitor domain in amyloid precursor protein reduces cellular mitochondrial enzymes expression and function
Li-Min Chua et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines
Diana F. Silva et al.
HUMAN MOLECULAR GENETICS (2013)
Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of -synuclein in Parkinsons disease models
Michaeline L. Hebron et al.
HUMAN MOLECULAR GENETICS (2013)
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease
Han-Yun Hsiao et al.
HUMAN MOLECULAR GENETICS (2013)
Astrocytes inhibit microglial surface expression of dendritic cell-related co-stimulatory molecules through a contact-mediated process
Giselles Acevedo et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells
Junghyung Park et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
Guo Zhang et al.
NATURE (2013)
Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance
Irina Lonskaya et al.
PLOS ONE (2013)
Isolation and Culture of Mouse Cortical Astrocytes
Sebastian Schildge et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
Inflammatory process in Alzheimer's Disease
Marco A. Meraz-Rios et al.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE (2013)
Strategic Role for Mitochondria in Alzheimer's Disease and Cancer
Louise Hedskog et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Antioxidant and bioenergetic coupling between neurons and astrocytes
Seila Fernandez-Fernandez et al.
BIOCHEMICAL JOURNAL (2012)
Bioenergetic role of mitochondrial fusion and fission
Benedikt Westermann
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)
Biogenesis and assembly of eukaryotic cytochrome c oxidase catalytic core
Ileana C. Soto et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)
Alzheimer disease as a vascular disorder: Where do mitochondria fit?
Sonia C. Correia et al.
EXPERIMENTAL GERONTOLOGY (2012)
Oligomers of beta-amyloid protein (Aβ1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factor-alpha, and a nuclear factor kappa-B mechanism in the rat brain
I. Carrero et al.
EXPERIMENTAL NEUROLOGY (2012)
NF-κB and the link between inflammation and cancer
Joseph A. DiDonato et al.
IMMUNOLOGICAL REVIEWS (2012)
Cancer: NF-κB regulates energy metabolism
Marta Moretti et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease
Baiyang Sheng et al.
JOURNAL OF NEUROCHEMISTRY (2012)
BAY 11-7082 Is a Broad-Spectrum Inhibitor with Anti-Inflammatory Activity against Multiple Targets
Jaehwi Lee et al.
MEDIATORS OF INFLAMMATION (2012)
Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr-Abl mutations and mutational analysis
Simona Soverini et al.
PHARMACOGENOMICS (2012)
Deceleration of Fusion-Fission Cycles Improves Mitochondrial Quality Control during Aging
Marc Thilo Figge et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
The Interplay Between Mitochondrial Dynamics and Mitophagy
Gilad Twig et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability
Artur Slupianek et al.
CANCER RESEARCH (2011)
Relationship between metabolism, sex and reproductive tactics in young Atlantic salmon (Salmo salar L.)
O. Rossignol et al.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2011)
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2011)
Neuronal c-Abl Overexpression Leads to Neuronal Loss and Neuroinflammation in the Mouse Forebrain
Sarah D. Schlatterer et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
c-Abl in Neurodegenerative Disease
Sarah D. Schlatterer et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease
Syed Z. Imam et al.
JOURNAL OF NEUROSCIENCE (2011)
NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration
Claudio Mauro et al.
NATURE CELL BIOLOGY (2011)
The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease
Kemal Ugur Tufekci et al.
PARKINSONS DISEASE (2011)
Functional complementation of mitochondrial DNAs: Mobilizing mitochondrial genetics against dysfunction
Eric A. Schon et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
Hsiuchen Chen et al.
CELL (2010)
The nuclear signaling of NF-kappa B: current knowledge, new insights, and future perspectives
Fengyi Wan et al.
CELL RESEARCH (2010)
AMP-activated protein kinase and its downstream transcriptional pathways
Carles Canto et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Regulation of mitochondrial biogenesis
Francois R. Jornayvaz et al.
ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)
Tau Phosphorylated at Tyrosine 394 is Found in Alzheimer's Disease Tangles and can be a Product of the Abl-Related Kinase, Arg
Matthew A. Tremblay et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Nuclear Factor-Kappa B Family Member RelB Inhibits Human Immunodeficiency Virus-1 Tat-Induced Tumor Necrosis Factor-Alpha Production
Michelle Kiebala et al.
PLOS ONE (2010)
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function
Han Seok Ko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Modeling Mitochondrial Bioenergetics with Integrated Volume Dynamics
Jason N. Bazil et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease
Gjumrakch Aliev et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Complex I Is Rate-limiting for Oxygen Consumption in the Nerve Terminal
Jayne E. Telford et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
Xinglong Wang et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
Xinglong Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
Increased Levels of Proinflammatory Cytokines in the Aged Rat Brain Attenuate Injury-induced Cytokine Response After Excitotoxic Damage
O. Campuzano et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
S. Hauptmann et al.
NEUROBIOLOGY OF AGING (2009)
NF-κB in the Nervous System
Barbara Kaltschmidt et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
NF-κB as a Critical Link Between Inflammation and Cancer
Michael Karin
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients
Xinglong Wang et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Transcriptional control of mitochondrial biogenesis:: the central role of PGC-1α
Renee Ventura-Clapier et al.
CARDIOVASCULAR RESEARCH (2008)
Nilotinib: A Second-Generation Tyrosine Kinase Inhibitor for the Treatment of Chronic Myelogenous Leukemia
David L. DeRemer et al.
CLINICAL THERAPEUTICS (2008)
Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
Philippe A. Parone et al.
PLOS ONE (2008)
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Joseph T. Rodgers et al.
FEBS LETTERS (2008)
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Sibylle Jaeger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Transcriptional coregulators in the control of energy homeostasis
Jerome N. Feige et al.
TRENDS IN CELL BIOLOGY (2007)
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Michelle L. Block et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Introduction to NF-κB:: players, pathways, perspectives
T. D. Gilmore
ONCOGENE (2006)
Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-κB activation
Kazuhiro Ishiguro et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Roles for NF-κB in nerve cell survival, plasticity, and disease
MP Mattson et al.
CELL DEATH AND DIFFERENTIATION (2006)
Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons:: implications for free radical generation and oxidative damage in disease progression
M Manczak et al.
HUMAN MOLECULAR GENETICS (2006)
Behavioural changes and psychological symptoms in dementia disorders
I McKeith et al.
LANCET NEUROLOGY (2005)
Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration
C Cunningham et al.
JOURNAL OF NEUROSCIENCE (2005)
Differentiated Alzheimer's disease transmitochondrial cybrid cell lines exhibit reduced organelle movement
PA Trimmer et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
HC Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
S Pich et al.
HUMAN MOLECULAR GENETICS (2005)
Metabolic control through the PGC-1 family of transcription coactivators
JD Lin et al.
CELL METABOLISM (2005)
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
P Bubber et al.
ANNALS OF NEUROLOGY (2005)
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
E Weisberg et al.
CANCER CELL (2005)
Activation of the transcription factor NF-kappa B by retrieval is required for long-term memory reconsolidation
E Merlo et al.
LEARNING & MEMORY (2005)
The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis
ER Chin
PROCEEDINGS OF THE NUTRITION SOCIETY (2004)
NF-κB-binding activity in an animal diet-induced overweightness model and the impact of subsequent energy restriction
O Lamas et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
NF-κB functions in synaptic signaling and behavior
MK Meffert et al.
NATURE NEUROSCIENCE (2003)
Systemic infection, interleukin 1β, and cognitive decline in Alzheimer's disease
C Holmes et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2003)
NF-κB and IκBα are found in the mitochondria -: Evidence for regulation of mitochondrial gene expression by NF-κB
PC Cogswell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
H Wu et al.
SCIENCE (2002)