Reactions of nickel(0) with organochlorides, organobromides, and organoiodides: mechanisms and structure/reactivity relationships

The reactions of nickel(0) complexes with organohalides have been reviewed. The review is divided according to the class of ligand that is present on nickel: phosphine, N-heterocyclic carbene, or bidentate nitrogen ligand. The preferred mechanism of reaction is often determined by a delicate balance of ligand and substrate structure, and relatively small changes can lead to large differences in behaviour. This will have an impact on the progress of catalytic reactions that use organohalide substrates, and may influence ligand selection and/or the scope and limitations of the reaction.

Automated summary

The review focuses on the reactions of nickel(0) complexes with organohalides, categorized based on the type of ligand present on nickel. The preferred reaction mechanism is influenced by a delicate balance of ligand and substrate structure, with small changes potentially leading to significant behavioral differences. This will impact the advancement of catalytic reactions using organohalide substrates and may affect ligand selection and the scope and limitations of the reactions.