Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

Antibiotic therapy comes with disturbances on human microbiota, resulting in changes of bacterial communities and thus leading to well-established health problems. In this study, we demonstrated that targeted teicoplanin administration maintains the faecal microbiota composition undisturbed in a mouse model while reaching therapeutic improvements for S. aureus infection.

Automated summary

Antibiotic therapy disrupts human microbiota, but targeted teicoplanin administration can maintain fecal microbiota composition undisturbed while improving therapeutic outcomes for S. aureus infection.