4.5 Article

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Pan-cancer analysis of whole genomes

Peter J. Campbell et al.

NATURE (2020)

Article Multidisciplinary Sciences

The repertoire of mutational signatures in human cancer

Ludmil B. Alexandrov et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

A Compendium of Mutational Signatures of Environmental Agents

Jill E. Kucab et al.

Article Biochemistry & Molecular Biology

Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study

Johan Staaf et al.

NATURE MEDICINE (2019)

Article Multidisciplinary Sciences

Pan-cancer whole-genome analyses of metastatic solid tumours

Peter Priestley et al.

NATURE (2019)

Article Multidisciplinary Sciences

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

Sharon Christenser et al.

NATURE COMMUNICATIONS (2019)

Article Medicine, Research & Experimental

The Impact of Next-Generation Sequencing on Cancer Genomics: From Discovery to Clinic

Elaine R. Mardis

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2019)

Article Biochemistry & Molecular Biology

Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers

Bettina Meier et al.

GENOME RESEARCH (2018)

Review Oncology

The emerging clinical relevance of genomics in cancer medicine

Michael F. Berger et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Article Multidisciplinary Sciences

Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair

N. J. Haradhvala et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Exploring patterns enriched in a dataset with contrastive principal component analysis

Abubakar Abid et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Validating the concept of mutational signatures with isogenic cell models

Xueqing Zou et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

A molecular portrait of microsatellite instability across multiple cancers

Isidro Cortes-Ciriano et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Comprehensive Analysis of Hypermutation in Human Cancer

Brittany B. Campbell et al.

Article Multidisciplinary Sciences

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Serena Nik-Zainal et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Classification and characterization of microsatellite instability across 18 cancer types

Ronald J. Hanse et al.

NATURE MEDICINE (2016)

Review Cell Biology

Repair Pathway Choices and Consequences at the Double-Strand Break

Raphael Ceccaldi et al.

TRENDS IN CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

The topography of mutational processes in breast cancer genomes

Sandro Morganella et al.

NATURE COMMUNICATIONS (2016)

Article Biochemical Research Methods

WGE: a CRISPR database for genome engineering

Alex Hodgkins et al.

BIOINFORMATICS (2015)

Article Multidisciplinary Sciences

MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations

Mi Ni Huang et al.

SCIENTIFIC REPORTS (2015)

Article Biochemical Research Methods

MSIsensor: microsatellite instability detection using paired tumor-normal sequence data

Beifang Niu et al.

BIOINFORMATICS (2014)

Article Medical Laboratory Technology

Microsatellite Instability Detection by Next Generation Sequencing

Stephen J. Salipante et al.

CLINICAL CHEMISTRY (2014)

Review Genetics & Heredity

Mechanisms underlying mutational signatures in human cancers

Thomas Helleday et al.

NATURE REVIEWS GENETICS (2014)

Article Medicine, Research & Experimental

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Thomas J. Cradick et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2014)

Review Multidisciplinary Sciences

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

Molly C. Kottemann et al.

NATURE (2013)

Article Multidisciplinary Sciences

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence

Julia Allgayer et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

Miyuki Bohgaki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

Francesca Mattiroli et al.

Article Biochemistry & Molecular Biology

Mutational Processes Molding the Genomes of 21 Breast Cancers

Serena Nik-Zainal et al.

Article Biochemistry & Molecular Biology

The Life History of 21 Breast Cancers

Serena Nik-Zainal et al.

Article Multidisciplinary Sciences

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Mechanism of mismatch recognition revealed by human MutS beta bound to unpaired DNA loops

Shikha Gupta et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Genetics & Heredity

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity

Scott A. Lujan et al.

PLOS GENETICS (2012)

Article Biochemical Research Methods

Bi-allelic gene targeting in mouse embryonic stem cells

Pen H. Tate et al.

METHODS (2011)

Article Biochemistry & Molecular Biology

Detection of Damaged DNA Bases by DNA Glycosylase Enzymes

Joshua I. Friedman et al.

BIOCHEMISTRY (2010)

Article Biochemical Research Methods

BEDTools: a flexible suite of utilities for comparing genomic features

Aaron R. Quinlan et al.

BIOINFORMATICS (2010)

Review Cell Biology

DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome

George Poulogiannis et al.

HISTOPATHOLOGY (2010)

Article Biochemistry & Molecular Biology

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

Emma Bolderson et al.

NUCLEIC ACIDS RESEARCH (2010)

Review Cell Biology

Transcription-coupled DNA repair: two decades of progress and surprises

Philip C. Hanawalt et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Multidisciplinary Sciences

Base-excision repair of oxidative DNA damage

Sheila S. David et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Structure of the human MutSα DNA lesion recognition complex

Joshua J. Warren et al.

MOLECULAR CELL (2007)

Article Multidisciplinary Sciences

A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex

Anirban Banerjee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Biotechnology & Applied Microbiology

Oxidative DNA damage and disease: induction, repair and significance

MD Evans et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2004)

Review Genetics & Heredity

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

DE Barnes et al.

ANNUAL REVIEW OF GENETICS (2004)

Article Biochemistry & Molecular Biology

Mechanism of 5 '-directed excision in human mismatch repair

J Genschel et al.

MOLECULAR CELL (2003)

Article Biochemistry & Molecular Biology

Yeast origins establish a strand bias for replicational mutagenesis

YI Pavlov et al.

MOLECULAR CELL (2002)

Article Biochemistry & Molecular Biology

Activation of human MutS homologs by 8-oxo-guanine DNA damage

A Mazurek et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Human DNA repair genes

RD Wood et al.

SCIENCE (2001)

Article Biotechnology & Applied Microbiology

Thymine-DNA glycosylase and G to A transition mutations at CpG sites

TR Waters et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2000)