相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pan-cancer analysis of whole genomes
Peter J. Campbell et al.
NATURE (2020)
The repertoire of mutational signatures in human cancer
Ludmil B. Alexandrov et al.
NATURE (2020)
Comprehensive analysis of indels in whole-genome microsatellite regions and microsatellite instability across 21 cancer types
Akihiro Fujimoto et al.
GENOME RESEARCH (2020)
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies
Andrea Degasperi et al.
NATURE CANCER (2020)
Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype
Judith E. Grolleman et al.
CANCER CELL (2019)
A Compendium of Mutational Signatures of Environmental Agents
Jill E. Kucab et al.
CELL (2019)
Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study
Johan Staaf et al.
NATURE MEDICINE (2019)
Pan-cancer whole-genome analyses of metastatic solid tumours
Peter Priestley et al.
NATURE (2019)
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer
Sharon Christenser et al.
NATURE COMMUNICATIONS (2019)
The Impact of Next-Generation Sequencing on Cancer Genomics: From Discovery to Clinic
Elaine R. Mardis
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2019)
Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers
Bettina Meier et al.
GENOME RESEARCH (2018)
The emerging clinical relevance of genomics in cancer medicine
Michael F. Berger et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair
N. J. Haradhvala et al.
NATURE COMMUNICATIONS (2018)
Exploring patterns enriched in a dataset with contrastive principal component analysis
Abubakar Abid et al.
NATURE COMMUNICATIONS (2018)
Validating the concept of mutational signatures with isogenic cell models
Xueqing Zou et al.
NATURE COMMUNICATIONS (2018)
MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML
Mathijs A. Sanders et al.
BLOOD (2018)
MSIpred: a python package for tumor microsatellite instability classification from tumor mutation annotation data using a support vector machine
Chen Wang et al.
SCIENTIFIC REPORTS (2018)
Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand
Maria A. Andrianova et al.
GENOME RESEARCH (2017)
Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas
Camilla Pilati et al.
JOURNAL OF PATHOLOGY (2017)
A molecular portrait of microsatellite instability across multiple cancers
Isidro Cortes-Ciriano et al.
NATURE COMMUNICATIONS (2017)
Comprehensive Analysis of Hypermutation in Human Cancer
Brittany B. Campbell et al.
CELL (2017)
Mismatch repair defects and Lynch syndrome: The role of the basic scientist in the battle against cancer
Christopher D. Heinen
DNA REPAIR (2016)
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Serena Nik-Zainal et al.
NATURE (2016)
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
Jaegil Kim et al.
NATURE GENETICS (2016)
Classification and characterization of microsatellite instability across 18 cancer types
Ronald J. Hanse et al.
NATURE MEDICINE (2016)
Repair Pathway Choices and Consequences at the Double-Strand Break
Raphael Ceccaldi et al.
TRENDS IN CELL BIOLOGY (2016)
The topography of mutational processes in breast cancer genomes
Sandro Morganella et al.
NATURE COMMUNICATIONS (2016)
WGE: a CRISPR database for genome engineering
Alex Hodgkins et al.
BIOINFORMATICS (2015)
MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations
Mi Ni Huang et al.
SCIENTIFIC REPORTS (2015)
Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr
Chukwuma A. Agu et al.
STEM CELL REPORTS (2015)
MSIsensor: microsatellite instability detection using paired tumor-normal sequence data
Beifang Niu et al.
BIOINFORMATICS (2014)
Microsatellite Instability Detection by Next Generation Sequencing
Stephen J. Salipante et al.
CLINICAL CHEMISTRY (2014)
Mechanisms underlying mutational signatures in human cancers
Thomas Helleday et al.
NATURE REVIEWS GENETICS (2014)
COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites
Thomas J. Cradick et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2014)
Analysis of Guanine Oxidation Products in Double-Stranded DNA and Proposed Guanine Oxidation Pathways in Single-Stranded, Double-Stranded or Quadruplex DNA
Masayuki Morikawa et al.
BIOMOLECULES (2014)
Fanconi anaemia and the repair of Watson and Crick DNA crosslinks
Molly C. Kottemann et al.
NATURE (2013)
Signatures of mutational processes in human cancer
Ludmil B. Alexandrov et al.
NATURE (2013)
Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence
Julia Allgayer et al.
NUCLEIC ACIDS RESEARCH (2013)
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
Miyuki Bohgaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mutation Rates, Spectra, and Genome-Wide Distribution of Spontaneous Mutations in Mismatch Repair Deficient Yeast
Gregory I. Lang et al.
G3-GENES GENOMES GENETICS (2013)
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
Francesca Mattiroli et al.
CELL (2012)
Mutational Processes Molding the Genomes of 21 Breast Cancers
Serena Nik-Zainal et al.
CELL (2012)
The Life History of 21 Breast Cancers
Serena Nik-Zainal et al.
CELL (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
Mechanism of mismatch recognition revealed by human MutS beta bound to unpaired DNA loops
Shikha Gupta et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity
Scott A. Lujan et al.
PLOS GENETICS (2012)
Bi-allelic gene targeting in mouse embryonic stem cells
Pen H. Tate et al.
METHODS (2011)
Detection of Damaged DNA Bases by DNA Glycosylase Enzymes
Joshua I. Friedman et al.
BIOCHEMISTRY (2010)
BEDTools: a flexible suite of utilities for comparing genomic features
Aaron R. Quinlan et al.
BIOINFORMATICS (2010)
DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome
George Poulogiannis et al.
HISTOPATHOLOGY (2010)
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
Emma Bolderson et al.
NUCLEIC ACIDS RESEARCH (2010)
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
Carsten Doil et al.
CELL (2009)
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
Grant S. Stewart et al.
CELL (2009)
The Polymerase η Translesion Synthesis DNA Polymerase Acts Independently of the Mismatch Repair System To Limit Mutagenesis Caused by 7,8-Dihydro-8-Oxoguanine in Yeast
Sarah V. Mudrak et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Oxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: Relationship between kinetics and distribution of alkali-labile lesions
Young Ae Lee et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
Transcription-coupled DNA repair: two decades of progress and surprises
Philip C. Hanawalt et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Base-excision repair of oxidative DNA damage
Sheila S. David et al.
NATURE (2007)
Structure of the human MutSα DNA lesion recognition complex
Joshua J. Warren et al.
MOLECULAR CELL (2007)
A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex
Anirban Banerjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA
A Banerjee et al.
NATURE (2005)
Oxidative DNA damage and disease: induction, repair and significance
MD Evans et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2004)
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
DE Barnes et al.
ANNUAL REVIEW OF GENETICS (2004)
Mechanism of 5 '-directed excision in human mismatch repair
J Genschel et al.
MOLECULAR CELL (2003)
Yeast origins establish a strand bias for replicational mutagenesis
YI Pavlov et al.
MOLECULAR CELL (2002)
Activation of human MutS homologs by 8-oxo-guanine DNA damage
A Mazurek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Thymine-DNA glycosylase and G to A transition mutations at CpG sites
TR Waters et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2000)
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
SD Bruner et al.
NATURE (2000)